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The structural basis for the selectivity of benzotriazole inhibitors of PTP1B.
Scapin G, Patel SB, Becker JW, Wang Q, Desponts C, Waddleton D, Skorey K, Cromlish W, Bayly C, Therien M, Gauthier JY, Li CS, Lau CK, Ramachandran C, Kennedy BP, Asante-Appiah E. Scapin G, et al. Biochemistry. 2003 Oct 7;42(39):11451-9. doi: 10.1021/bi035098j. Biochemistry. 2003. PMID: 14516196
Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase.
Asante-Appiah E, Patel S, Desponts C, Taylor JM, Lau C, Dufresne C, Therien M, Friesen R, Becker JW, Leblanc Y, Kennedy BP, Scapin G. Asante-Appiah E, et al. Among authors: scapin g. J Biol Chem. 2006 Mar 24;281(12):8010-5. doi: 10.1074/jbc.M511827200. Epub 2006 Jan 6. J Biol Chem. 2006. PMID: 16407290 Free article.
111 results