Klockgether T - Search Results

1

The human MJD gene: genomic structure and functional characterization of the promoter region.

Schmitt I, Evert BO, Khazneh H, Klockgether T, Wuellner U. Schmitt I, et al. Among authors: klockgether t. Gene. 2003 Sep 18;314:81-8. doi: 10.1016/s0378-1119(03)00706-6. Gene. 2003. PMID: 14527720

2

Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3.

Evert BO, Vogt IR, Vieira-Saecker AM, Ozimek L, de Vos RA, Brunt ER, Klockgether T, Wüllner U. Evert BO, et al. Among authors: klockgether t. J Neuropathol Exp Neurol. 2003 Oct;62(10):1006-18. doi: 10.1093/jnen/62.10.1006. J Neuropathol Exp Neurol. 2003. PMID: 14575237

3

Potassium channel dysfunction and depolarized resting membrane potential in a cell model of SCA3.

Jeub M, Herbst M, Spauschus A, Fleischer H, Klockgether T, Wuellner U, Evert BO. Jeub M, et al. Among authors: klockgether t. Exp Neurol. 2006 Sep;201(1):182-92. doi: 10.1016/j.expneurol.2006.03.029. Epub 2006 Jun 12. Exp Neurol. 2006. PMID: 16765348

4

Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation.

Evert BO, Araujo J, Vieira-Saecker AM, de Vos RA, Harendza S, Klockgether T, Wüllner U. Evert BO, et al. Among authors: klockgether t. J Neurosci. 2006 Nov 1;26(44):11474-86. doi: 10.1523/JNEUROSCI.2053-06.2006. J Neurosci. 2006. PMID: 17079677 Free PMC article.

5

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination.

Schmitt I, Linden M, Khazneh H, Evert BO, Breuer P, Klockgether T, Wuellner U. Schmitt I, et al. Among authors: klockgether t. Biochem Biophys Res Commun. 2007 Oct 26;362(3):734-9. doi: 10.1016/j.bbrc.2007.08.062. Epub 2007 Aug 23. Biochem Biophys Res Commun. 2007. PMID: 17764659

6

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.

Araujo J, Breuer P, Dieringer S, Krauss S, Dorn S, Zimmermann K, Pfeifer A, Klockgether T, Wuellner U, Evert BO. Araujo J, et al. Among authors: klockgether t. Hum Mol Genet. 2011 Aug 1;20(15):2928-41. doi: 10.1093/hmg/ddr197. Epub 2011 May 2. Hum Mol Genet. 2011. PMID: 21536589

7

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.

Koch P, Breuer P, Peitz M, Jungverdorben J, Kesavan J, Poppe D, Doerr J, Ladewig J, Mertens J, Tüting T, Hoffmann P, Klockgether T, Evert BO, Wüllner U, Brüstle O. Koch P, et al. Among authors: klockgether t. Nature. 2011 Nov 23;480(7378):543-6. doi: 10.1038/nature10671. Nature. 2011. PMID: 22113611

8

High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells.

Evert BO, Wüllner U, Schulz JB, Weller M, Groscurth P, Trottier Y, Brice A, Klockgether T. Evert BO, et al. Among authors: klockgether t. Hum Mol Genet. 1999 Jul;8(7):1169-76. doi: 10.1093/hmg/8.7.1169. Hum Mol Genet. 1999. PMID: 10369861

9

The molecular biology of the autosomal-dominant cerebellar ataxias.

Klockgether T, Wüllner U, Spauschus A, Evert B. Klockgether T, et al. Mov Disord. 2000 Jul;15(4):604-12. doi: 10.1002/1531-8257(200007)15:4<604::aid-mds1004>3.0.co;2-k. Mov Disord. 2000. PMID: 10928570 Review.

10

Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains.

Evert BO, Vogt IR, Kindermann C, Ozimek L, de Vos RA, Brunt ER, Schmitt I, Klockgether T, Wüllner U. Evert BO, et al. Among authors: klockgether t. J Neurosci. 2001 Aug 1;21(15):5389-96. doi: 10.1523/JNEUROSCI.21-15-05389.2001. J Neurosci. 2001. PMID: 11466410 Free PMC article.

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