Grieco P - Search Results

1

Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.

Grieco P, Balse-Srinivasan P, Han G, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Grieco P, et al. J Pept Res. 2003 Nov;62(5):199-206. doi: 10.1034/j.1399-3011.2003.00087.x. J Pept Res. 2003. PMID: 14531843

2

Design and synthesis of highly potent and selective melanotropin analogues of SHU9119 modified at position 6.

Grieco P, Han G, Weinberg D, Van der Ploeg LH, Hruby VJ. Grieco P, et al. Biochem Biophys Res Commun. 2002 Apr 12;292(4):1075-80. doi: 10.1006/bbrc.2002.6739. Biochem Biophys Res Commun. 2002. PMID: 11944925

3

Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors.

Kavarana MJ, Trivedi D, Cai M, Ying J, Hammer M, Cabello C, Grieco P, Han G, Hruby VJ. Kavarana MJ, et al. Among authors: grieco p. J Med Chem. 2002 Jun 6;45(12):2644-50. doi: 10.1021/jm020021z. J Med Chem. 2002. PMID: 12036373

4

Structure-activity studies of the melanocortin peptides: discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors.

Grieco P, Lavecchia A, Cai M, Trivedi D, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Grieco P, et al. J Med Chem. 2002 Nov 21;45(24):5287-94. doi: 10.1021/jm0202526. J Med Chem. 2002. PMID: 12431055

5

Exploring the stereostructural requirements of peptide ligands for the melanocortin receptors.

Hruby VJ, Cai M, Grieco P, Han G, Kavarana M, Trivedi D. Hruby VJ, et al. Among authors: grieco p. Ann N Y Acad Sci. 2003 Jun;994:12-20. doi: 10.1111/j.1749-6632.2003.tb03157.x. Ann N Y Acad Sci. 2003. PMID: 12851293

6

Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R.

Balse-Srinivasan P, Grieco P, Cai M, Trivedi D, Hruby VJ. Balse-Srinivasan P, et al. Among authors: grieco p. J Med Chem. 2003 Aug 14;46(17):3728-33. doi: 10.1021/jm030111j. J Med Chem. 2003. PMID: 12904077

7

Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues.

Balse-Srinivasan P, Grieco P, Cai M, Trivedi D, Hruby VJ. Balse-Srinivasan P, et al. Among authors: grieco p. J Med Chem. 2003 Nov 6;46(23):4965-73. doi: 10.1021/jm030119t. J Med Chem. 2003. PMID: 14584947

8

Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position.

Grieco P, Cai M, Mayorov AV, Trivedi D, Hruby VJ. Grieco P, et al. Peptides. 2006 Feb;27(2):472-81. doi: 10.1016/j.peptides.2005.01.032. Epub 2005 Nov 21. Peptides. 2006. PMID: 16303211 Free PMC article.

9

Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.

Grieco P, Cai M, Han G, Trivedi D, Campiglia P, Novellino E, Hruby VJ. Grieco P, et al. Peptides. 2007 Jun;28(6):1191-6. doi: 10.1016/j.peptides.2007.02.012. Epub 2007 Mar 1. Peptides. 2007. PMID: 17482720 Free PMC article.

10

Substitution of arginine with proline and proline derivatives in melanocyte-stimulating hormones leads to selectivity for human melanocortin 4 receptor.

Qu H, Cai M, Mayorov AV, Grieco P, Zingsheim M, Trivedi D, Hruby VJ. Qu H, et al. Among authors: grieco p. J Med Chem. 2009 Jun 25;52(12):3627-35. doi: 10.1021/jm801300c. J Med Chem. 2009. PMID: 19473029 Free PMC article.

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