Van der Ploeg LH - Search Results

1

Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.

Grieco P, Balse-Srinivasan P, Han G, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Grieco P, et al. Among authors: van der ploeg lh. J Pept Res. 2003 Nov;62(5):199-206. doi: 10.1034/j.1399-3011.2003.00087.x. J Pept Res. 2003. PMID: 14531843

2

Design and synthesis of highly potent and selective melanotropin analogues of SHU9119 modified at position 6.

Grieco P, Han G, Weinberg D, Van der Ploeg LH, Hruby VJ. Grieco P, et al. Among authors: van der ploeg lh. Biochem Biophys Res Commun. 2002 Apr 12;292(4):1075-80. doi: 10.1006/bbrc.2002.6739. Biochem Biophys Res Commun. 2002. PMID: 11944925

3

Synthesis and biological evaluation on hMC3, hMC4 and hMC5 receptors of gamma-MSH analogs substituted with L-alanine.

Grieco P, Balse-Srinivasan P, Han G, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Grieco P, et al. Among authors: van der ploeg lh. J Pept Res. 2002 May;59(5):203-10. doi: 10.1034/j.1399-3011.2002.01966.x. J Pept Res. 2002. PMID: 11966977

4

Structure-activity studies of the melanocortin peptides: discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors.

Grieco P, Lavecchia A, Cai M, Trivedi D, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Grieco P, et al. Among authors: van der ploeg lh. J Med Chem. 2002 Nov 21;45(24):5287-94. doi: 10.1021/jm0202526. J Med Chem. 2002. PMID: 12431055

5

Analogs of MTII, lactam derivatives of alpha-melanotropin, modified at the N-terminus, and their selectivity at human melanocortin receptors 3, 4, and 5.

Bednarek MA, Macneil T, Kalyani RN, Tang R, Van der Ploeg LH, Weinberg DH. Bednarek MA, et al. Among authors: van der ploeg lh. Biochem Biophys Res Commun. 1999 Jul 22;261(1):209-13. doi: 10.1006/bbrc.1999.0981. Biochem Biophys Res Commun. 1999. PMID: 10405347

6

Structure-activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat.

Ye Z, MacNeil T, Weinberg DH, Kalyani RN, Tang R, Strack AM, Murphy BA, Mosley RT, Euan MacIntyre D, Van der Ploeg LH, Patchett AA, Wyvratt MJ, Nargund RP. Ye Z, et al. Among authors: van der ploeg lh. Peptides. 2005 Oct;26(10):2017-25. doi: 10.1016/j.peptides.2004.12.035. Peptides. 2005. PMID: 15993513

7

Analogs of lactam derivatives of alpha-melanotropin with basic and acidic residues.

Bednarek MA, MacNeil T, Kalyani RN, Tang R, Van der Ploeg LH, Weinberg DH. Bednarek MA, et al. Among authors: van der ploeg lh. Biochem Biophys Res Commun. 2000 May 27;272(1):23-8. doi: 10.1006/bbrc.2000.2589. Biochem Biophys Res Commun. 2000. PMID: 10872798

8

Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro.

Bednarek MA, MacNeil T, Tang R, Kalyani RN, Van der Ploeg LH, Weinberg DH. Bednarek MA, et al. Among authors: van der ploeg lh. Biochem Biophys Res Commun. 2001 Aug 24;286(3):641-5. doi: 10.1006/bbrc.2001.5444. Biochem Biophys Res Commun. 2001. PMID: 11511108

9

Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro.

Bednarek MA, MacNeil T, Kalyani RN, Tang R, Van der Ploeg LH, Weinberg DH. Bednarek MA, et al. Among authors: van der ploeg lh. J Med Chem. 2001 Oct 25;44(22):3665-72. doi: 10.1021/jm010165y. J Med Chem. 2001. PMID: 11606131

10

Design and syntheses of melanocortin subtype-4 receptor agonists. Part 2: discovery of the dihydropyridazinone motif.

Ujjainwalla F, Warner D, Snedden C, Grisson RD, Walsh TF, Wyvratt MJ, Kalyani RN, Macneil T, Tang R, Weinberg DH, Van der Ploeg L, Goulet MT. Ujjainwalla F, et al. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4023-8. doi: 10.1016/j.bmcl.2005.06.033. Bioorg Med Chem Lett. 2005. PMID: 16005624

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