Parlow JJ - Search Results

1

Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue factor VIIa complex.

Parlow JJ, Kurumbail RG, Stegeman RA, Stevens AM, Stallings WC, South MS. Parlow JJ, et al. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3721-5. doi: 10.1016/j.bmcl.2003.08.002. Bioorg Med Chem Lett. 2003. PMID: 14552766

2

Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.

South MS, Case BL, Wood RS, Jones DE, Hayes MJ, Girard TJ, Lachance RM, Nicholson NS, Clare M, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. South MS, et al. Among authors: parlow jj. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2319-25. doi: 10.1016/s0960-894x(03)00410-4. Bioorg Med Chem Lett. 2003. PMID: 12824026

3

Polymer-assisted solution-phase (PASP) parallel synthesis of an alpha-ketothiazole library as tissue factor VIIa inhibitors.

South MS, Dice TA, Girard TJ, Lachance RM, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. South MS, et al. Among authors: parlow jj. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2363-7. doi: 10.1016/s0960-894x(03)00398-6. Bioorg Med Chem Lett. 2003. PMID: 12824035

4

Polymer-assisted solution-phase library synthesis and crystal structure of alpha-ketothiazoles as tissue factor VIIa inhibitors.

Parlow JJ, Dice TA, Lachance RM, Girard TJ, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. J Med Chem. 2003 Sep 11;46(19):4043-9. doi: 10.1021/jm030130t. J Med Chem. 2003. PMID: 12954057

5

Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.

Parlow JJ, Case BL, Dice TA, Fenton RL, Hayes MJ, Jones DE, Neumann WL, Wood RS, Lachance RM, Girard TJ, Nicholson NS, Clare M, Stegeman RA, Stevens AM, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. J Med Chem. 2003 Sep 11;46(19):4050-62. doi: 10.1021/jm030131l. J Med Chem. 2003. PMID: 12954058

6

Synthesis and crystal structures of substituted benzenes and benzoquinones as tissue factor VIIa inhibitors.

Parlow JJ, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. J Med Chem. 2003 Sep 25;46(20):4297-312. doi: 10.1021/jm030233b. J Med Chem. 2003. PMID: 13678408

7

Design, synthesis, and crystal structure of selective 2-pyridone tissue factor VIIa inhibitors.

Parlow JJ, Kurumbail RG, Stegeman RA, Stevens AM, Stallings WC, South MS. Parlow JJ, et al. J Med Chem. 2003 Oct 23;46(22):4696-701. doi: 10.1021/jm0301686. J Med Chem. 2003. PMID: 14561089

8

Pharmacological interruption of acute thrombus formation with minimal hemorrhagic complications by a small molecule tissue factor/factor VIIa inhibitor: comparison to factor Xa and thrombin inhibition in a nonhuman primate thrombosis model.

Suleymanov OD, Szalony JA, Salyers AK, LaChance RM, Parlow JJ, South MS, Wood RS, Nicholson NS. Suleymanov OD, et al. Among authors: parlow jj. J Pharmacol Exp Ther. 2003 Sep;306(3):1115-21. doi: 10.1124/jpet.103.052779. Epub 2003 Jun 26. J Pharmacol Exp Ther. 2003. PMID: 12829728

9

Assessment of bleeding propensity in non-human primates by combination of selective tissue factor/VIIa inhibition and aspirin compared to warfarin and aspirin treatment.

Salyers AK, Szalony JA, Suleymanov OD, Parlow JJ, Wood RS, South MS, Nicholson NS. Salyers AK, et al. Among authors: parlow jj. Pharmacology. 2004 Feb;70(2):100-6. doi: 10.1159/000074674. Pharmacology. 2004. PMID: 14685013

10

Administration of a small molecule tissue factor/factor VIIa inhibitor in a non-human primate thrombosis model of venous thrombosis: effects on thrombus formation and bleeding time.

Szalony JA, Suleymanov OD, Salyers AK, Panzer-Knodle SG, Blom JD, LaChance RM, Case BL, Parlow JJ, South MS, Wood RS, Nicholson NS. Szalony JA, et al. Among authors: parlow jj. Thromb Res. 2003;112(3):167-74. doi: 10.1016/j.thromres.2003.10.017. Thromb Res. 2003. PMID: 14967414

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