Urbina J - Search Results

1

Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi.

Magaraci F, Jimenez CJ, Rodrigues C, Rodrigues JC, Braga MV, Yardley V, de Luca-Fradley K, Croft SL, de Souza W, Ruiz-Perez LM, Urbina J, Gonzalez Pacanowska D, Gilbert IH. Magaraci F, et al. Among authors: urbina j. J Med Chem. 2003 Oct 23;46(22):4714-27. doi: 10.1021/jm021114j. J Med Chem. 2003. PMID: 14561091

2

Quinuclidine derivatives as potential antiparasitics.

Cammerer SB, Jimenez C, Jones S, Gros L, Lorente SO, Rodrigues C, Rodrigues JC, Caldera A, Ruiz Perez LM, da Souza W, Kaiser M, Brun R, Urbina JA, Gonzalez Pacanowska D, Gilbert IH. Cammerer SB, et al. Antimicrob Agents Chemother. 2007 Nov;51(11):4049-61. doi: 10.1128/AAC.00205-07. Epub 2007 Aug 20. Antimicrob Agents Chemother. 2007. PMID: 17709461 Free PMC article.

3

Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates.

Hudock MP, Sanz-Rodríguez CE, Song Y, Chan JM, Zhang Y, Odeh S, Kosztowski T, Leon-Rossell A, Concepción JL, Yardley V, Croft SL, Urbina JA, Oldfield E. Hudock MP, et al. Among authors: urbina ja. J Med Chem. 2006 Jan 12;49(1):215-23. doi: 10.1021/jm0582625. J Med Chem. 2006. PMID: 16392806

4

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action.

Gros L, Castillo-Acosta VM, Jiménez Jiménez C, Sealey-Cardona M, Vargas S, Manuel Estévez A, Yardley V, Rattray L, Croft SL, Ruiz-Perez LM, Urbina JA, Gilbert IH, González-Pacanowska D. Gros L, et al. Antimicrob Agents Chemother. 2006 Aug;50(8):2595-601. doi: 10.1128/AAC.01508-05. Antimicrob Agents Chemother. 2006. PMID: 16870747 Free PMC article.

5

Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis.

Lorente SO, Rodrigues JC, Jiménez Jiménez C, Joyce-Menekse M, Rodrigues C, Croft SL, Yardley V, de Luca-Fradley K, Ruiz-Pérez LM, Urbina J, de Souza W, González Pacanowska D, Gilbert IH. Lorente SO, et al. Among authors: urbina j. Antimicrob Agents Chemother. 2004 Aug;48(8):2937-50. doi: 10.1128/AAC.48.8.2937-2950.2004. Antimicrob Agents Chemother. 2004. PMID: 15273104 Free PMC article.

6

Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa.

Orenes Lorente S, Gómez R, Jiménez C, Cammerer S, Yardley V, de Luca-Fradley K, Croft SL, Ruiz Perez LM, Urbina J, Gonzalez Pacanowska D, Gilbert IH. Orenes Lorente S, et al. Among authors: urbina j. Bioorg Med Chem. 2005 May 16;13(10):3519-29. doi: 10.1016/j.bmc.2005.02.060. Bioorg Med Chem. 2005. PMID: 15848765

7

Effects of squalene synthase inhibitors on the growth and ultrastructure of Trypanosoma cruzi.

Braga MV, Urbina JA, de Souza W. Braga MV, et al. Int J Antimicrob Agents. 2004 Jul;24(1):72-8. doi: 10.1016/j.ijantimicag.2003.12.009. Int J Antimicrob Agents. 2004. PMID: 15225865

8

Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy.

Martin MB, Grimley JS, Lewis JC, Heath HT 3rd, Bailey BN, Kendrick H, Yardley V, Caldera A, Lira R, Urbina JA, Moreno SN, Docampo R, Croft SL, Oldfield E. Martin MB, et al. Among authors: urbina ja. J Med Chem. 2001 Mar 15;44(6):909-16. doi: 10.1021/jm0002578. J Med Chem. 2001. PMID: 11300872

9

Antiproliferative and ultrastructural effects of BPQ-OH, a specific inhibitor of squalene synthase, on Leishmania amazonensis.

Rodrigues JC, Urbina JA, de Souza W. Rodrigues JC, et al. Exp Parasitol. 2005 Dec;111(4):230-8. doi: 10.1016/j.exppara.2005.08.006. Epub 2005 Sep 29. Exp Parasitol. 2005. PMID: 16198340

10

Alterations on the growth and ultrastructure of Leishmania chagasi induced by squalene synthase inhibitors.

Granthon AC, Braga MV, Rodrigues JC, Cammerer S, Lorente SO, Gilbert IH, Urbina JA, de Souza W. Granthon AC, et al. Vet Parasitol. 2007 May 15;146(1-2):25-34. doi: 10.1016/j.vetpar.2006.12.022. Epub 2007 Mar 23. Vet Parasitol. 2007. PMID: 17367936

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