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Cdk2 knockout mice are viable.
Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Berthet C, et al. Among authors: kaldis p. Curr Biol. 2003 Oct 14;13(20):1775-85. doi: 10.1016/j.cub.2003.09.024. Curr Biol. 2003. PMID: 14561402 Free article.
Cell cycle sibling rivalry: Cdc2 vs. Cdk2.
Kaldis P, Aleem E. Kaldis P, et al. Cell Cycle. 2005 Nov;4(11):1491-4. doi: 10.4161/cc.4.11.2124. Epub 2005 Nov 29. Cell Cycle. 2005. PMID: 16258277 Review.
CDK2 is required by MYC to induce apoptosis.
Deb-Basu D, Aleem E, Kaldis P, Felsher DW. Deb-Basu D, et al. Among authors: kaldis p. Cell Cycle. 2006 Jun;5(12):1342-7. doi: 10.4161/cc.5.12.2859. Epub 2006 Jun 15. Cell Cycle. 2006. PMID: 16760655
Mouse models of cell cycle regulators: new paradigms.
Aleem E, Kaldis P. Aleem E, et al. Among authors: kaldis p. Results Probl Cell Differ. 2006;42:271-328. doi: 10.1007/400_023. Results Probl Cell Differ. 2006. PMID: 16903215 Review.
152 results