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In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor.
Eefting D, de Vries MR, Grimbergen JM, Karper JC, van Bockel JH, Quax PH. Eefting D, et al. Among authors: grimbergen jm. J Vasc Surg. 2010 Feb;51(2):429-37. doi: 10.1016/j.jvs.2009.09.026. Epub 2009 Dec 24. J Vasc Surg. 2010. PMID: 20036101 Free article.
Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1.
Lamfers ML, Grimbergen JM, Aalders MC, Havenga MJ, de Vries MR, Huisman LG, van Hinsbergh VW, Quax PH. Lamfers ML, et al. Among authors: grimbergen jm. Circ Res. 2002 Nov 15;91(10):945-52. doi: 10.1161/01.res.0000041418.51906.57. Circ Res. 2002. PMID: 12433840
Anti-MCP-1 gene therapy inhibits vascular smooth muscle cells proliferation and attenuates vein graft thickening both in vitro and in vivo.
Schepers A, Eefting D, Bonta PI, Grimbergen JM, de Vries MR, van Weel V, de Vries CJ, Egashira K, van Bockel JH, Quax PH. Schepers A, et al. Among authors: grimbergen jm. Arterioscler Thromb Vasc Biol. 2006 Sep;26(9):2063-9. doi: 10.1161/01.ATV.0000235694.69719.e2. Epub 2006 Jul 6. Arterioscler Thromb Vasc Biol. 2006. PMID: 16825596
47 results