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Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus.
Mummidi S, Bamshad M, Ahuja SS, Gonzalez E, Feuillet PM, Begum K, Galvis MC, Kostecki V, Valente AJ, Murthy KK, Haro L, Dolan MJ, Allan JS, Ahuja SK. Mummidi S, et al. Among authors: ahuja sk, ahuja ss. J Biol Chem. 2000 Jun 23;275(25):18946-61. doi: 10.1074/jbc.M000169200. J Biol Chem. 2000. PMID: 10747879 Free article.
CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation.
Sato N, Ahuja SK, Quinones M, Kostecki V, Reddick RL, Melby PC, Kuziel WA, Ahuja SS. Sato N, et al. Among authors: ahuja sk, ahuja ss. J Exp Med. 2000 Jul 17;192(2):205-18. doi: 10.1084/jem.192.2.205. J Exp Med. 2000. PMID: 10899907 Free PMC article.
130 results