Nazi I - Search Results

1

Simultaneous in vitro assay of the first four enzymes in the fungal aspartate pathway identifies a new class of aspartate kinase inhibitor.

Bareich DC, Nazi I, Wright GD. Bareich DC, et al. Among authors: nazi i. Chem Biol. 2003 Oct;10(10):967-73. doi: 10.1016/j.chembiol.2003.09.016. Chem Biol. 2003. PMID: 14583263 No abstract available.

2

Small molecule functional discrimination of the kinases required for the microbial synthesis of threonine and isoleucine.

Bareich D, Koteva K, Nazi I, Wright GD. Bareich D, et al. Among authors: nazi i. Bioorg Med Chem. 2004 Feb 15;12(4):807-15. doi: 10.1016/j.bmc.2003.10.042. Bioorg Med Chem. 2004. PMID: 14759741

3

New phenolic inhibitors of yeast homoserine dehydrogenase.

Ejim L, Mirza IA, Capone C, Nazi I, Jenkins S, Chee GL, Berghuis AM, Wright GD. Ejim L, et al. Among authors: nazi i. Bioorg Med Chem. 2004 Jul 15;12(14):3825-30. doi: 10.1016/j.bmc.2004.05.009. Bioorg Med Chem. 2004. PMID: 15210149

4

One-pot chemoenzymatic preparation of coenzyme A analogues.

Nazi I, Koteva KP, Wright GD. Nazi I, et al. Anal Biochem. 2004 Jan 1;324(1):100-5. doi: 10.1016/j.ab.2003.09.005. Anal Biochem. 2004. PMID: 14654051

5

Catalytic mechanism of fungal homoserine transacetylase.

Nazi I, Wright GD. Nazi I, et al. Biochemistry. 2005 Oct 18;44(41):13560-6. doi: 10.1021/bi0514764. Biochemistry. 2005. PMID: 16216079

6

Role of homoserine transacetylase as a new target for antifungal agents.

Nazi I, Scott A, Sham A, Rossi L, Williamson PR, Kronstad JW, Wright GD. Nazi I, et al. Antimicrob Agents Chemother. 2007 May;51(5):1731-6. doi: 10.1128/AAC.01400-06. Epub 2007 Mar 12. Antimicrob Agents Chemother. 2007. PMID: 17353245 Free PMC article.

7

A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor.

Koteva K, Hong HJ, Wang XD, Nazi I, Hughes D, Naldrett MJ, Buttner MJ, Wright GD. Koteva K, et al. Among authors: nazi i. Nat Chem Biol. 2010 May;6(5):327-9. doi: 10.1038/nchembio.350. Epub 2010 Apr 11. Nat Chem Biol. 2010. PMID: 20383152

8

Identification and characterization of new inhibitors of fungal homoserine kinase.

De Pascale G, Griffiths EJ, Shakya T, Nazi I, Wright GD. De Pascale G, et al. Among authors: nazi i. Chembiochem. 2011 May 16;12(8):1179-82. doi: 10.1002/cbic.201100121. Epub 2011 Apr 28. Chembiochem. 2011. PMID: 21538764 No abstract available.

9

β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents.

De Pascale G, Nazi I, Harrison PH, Wright GD. De Pascale G, et al. Among authors: nazi i. J Antibiot (Tokyo). 2011 Jul;64(7):483-7. doi: 10.1038/ja.2011.37. Epub 2011 Apr 27. J Antibiot (Tokyo). 2011. PMID: 21522158

10

Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of alpha/beta-hydrolases.

Mirza IA, Nazi I, Korczynska M, Wright GD, Berghuis AM. Mirza IA, et al. Among authors: nazi i. Biochemistry. 2005 Dec 6;44(48):15768-73. doi: 10.1021/bi051951y. Biochemistry. 2005. PMID: 16313180

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