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Potent antitumor activity of a novel cationic pyridinium-ceramide alone or in combination with gemcitabine against human head and neck squamous cell carcinomas in vitro and in vivo.
Senkal CE, Ponnusamy S, Rossi MJ, Sundararaj K, Szulc Z, Bielawski J, Bielawska A, Meyer M, Cobanoglu B, Koybasi S, Sinha D, Day TA, Obeid LM, Hannun YA, Ogretmen B. Senkal CE, et al. Among authors: bielawski j. J Pharmacol Exp Ther. 2006 Jun;317(3):1188-99. doi: 10.1124/jpet.106.101949. Epub 2006 Mar 1. J Pharmacol Exp Ther. 2006. PMID: 16510697
Golgi fragmentation is associated with ceramide-induced cellular effects.
Hu W, Xu R, Zhang G, Jin J, Szulc ZM, Bielawski J, Hannun YA, Obeid LM, Mao C. Hu W, et al. Among authors: bielawski j. Mol Biol Cell. 2005 Mar;16(3):1555-67. doi: 10.1091/mbc.e04-07-0594. Epub 2005 Jan 12. Mol Biol Cell. 2005. PMID: 15647381 Free PMC article.
327 results