Barrish JC - Search Results

1

Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56(Lck).

Wityak J, Das J, Moquin RV, Shen Z, Lin J, Chen P, Doweyko AM, Pitt S, Pang S, Shen DR, Fang Q, de Fex HF, Schieven GL, Kanner SB, Barrish JC. Wityak J, et al. Among authors: barrish jc. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4007-10. doi: 10.1016/j.bmcl.2003.08.054. Bioorg Med Chem Lett. 2003. PMID: 14592495

2

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

Bechtold CM, Patick AK, Alam M, Greytok J, Tino JA, Chen P, Gordon E, Ahmad S, Barrish JC, Zahler R, et al. Bechtold CM, et al. Among authors: barrish jc. Antimicrob Agents Chemother. 1995 Feb;39(2):374-9. doi: 10.1128/AAC.39.2.374. Antimicrob Agents Chemother. 1995. PMID: 7726501 Free PMC article.

3

Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR.

Barrish JC, Gordon E, Alam M, Lin PF, Bisacchi GS, Chen P, Cheng PT, Fritz AW, Greytok JA, Hermsmeier MA. Barrish JC, et al. J Med Chem. 1994 Jun 10;37(12):1758-68. doi: 10.1021/jm00038a005. J Med Chem. 1994. PMID: 8021916

4

1-Benzazepin-2-one calcium channel blockers--VI. Receptor-binding model and possible relationship to desmethoxyverapamil.

Kimball SD, Hunt JT, Barrish JC, Das J, Floyd DM, Lago MW, Lee VG, Spergel SH, Moreland S, Hedberg SA, et al. Kimball SD, et al. Among authors: barrish jc. Bioorg Med Chem. 1993 Oct;1(4):285-307. doi: 10.1016/s0968-0896(00)82134-3. Bioorg Med Chem. 1993. PMID: 8081860

5

Conformationally constrained calcium channel blockers: novel mimics of 1-benzazepin-2-ones.

Barrish JC, Spergel SH, Moreland S, Grover G, Hedberg SA, Pudzianowski AT, Gougoutas JZ, Malley MF. Barrish JC, et al. Bioorg Med Chem. 1993 Oct;1(4):309-25. doi: 10.1016/s0968-0896(00)82135-5. Bioorg Med Chem. 1993. PMID: 8081861

6

Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists.

Misra RN, Brown BR, Sher PM, Patel MM, Hall SE, Han WC, Barrish JC, Kocy O, Harris DN, Goldenberg HJ, et al. Misra RN, et al. Among authors: barrish jc. J Med Chem. 1993 May 14;36(10):1401-17. doi: 10.1021/jm00062a013. J Med Chem. 1993. PMID: 8496908

7

Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity.

Chen P, Cheng PT, Alam M, Beyer BD, Bisacchi GS, Dejneka T, Evans AJ, Greytok JA, Hermsmeier MA, Humphreys WG, Jacobs GA, Kocy O, Lin PF, Lis KA, Marella MA, Ryono DE, Sheaffer AK, Spergel SH, Sun CQ, Tino JA, Vite G, Colonno RJ, Zahler R, Barrish JC. Chen P, et al. Among authors: barrish jc. J Med Chem. 1996 May 10;39(10):1991-2007. doi: 10.1021/jm950717a. J Med Chem. 1996. PMID: 8642558

8

Biphenylsulfonamide endothelin receptor antagonists. 2. Discovery of 4'-oxazolyl biphenylsulfonamides as a new class of potent, highly selective ET(A) antagonists.

Murugesan N, Gu Z, Stein PD, Spergel S, Mathur A, Leith L, Liu EC, Zhang R, Bird E, Waldron T, Marino A, Morrison RA, Webb ML, Moreland S, Barrish JC. Murugesan N, et al. Among authors: barrish jc. J Med Chem. 2000 Aug 10;43(16):3111-7. doi: 10.1021/jm000105c. J Med Chem. 2000. PMID: 10956219

9

Biphenylsulfonamide endothelin receptor antagonists. Part 3: structure-activity relationship of 4'-heterocyclic biphenylsulfonamides.

Murugesan N, Gu Z, Stein PD, Spergel S, Bisaha S, Liu EC, Zhang R, Webb ML, Moreland S, Barrish JC. Murugesan N, et al. Among authors: barrish jc. Bioorg Med Chem Lett. 2002 Feb 25;12(4):517-20. doi: 10.1016/s0960-894x(01)00791-0. Bioorg Med Chem Lett. 2002. PMID: 11844662

10

Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56(Lck).

Chen P, Norris D, Iwanowicz EJ, Spergel SH, Lin J, Gu HH, Shen Z, Wityak J, Lin TA, Pang S, De Fex HF, Pitt S, Shen DR, Doweyko AM, Bassolino DA, Roberge JY, Poss MA, Chen BC, Schieven GL, Barrish JC. Chen P, et al. Among authors: barrish jc. Bioorg Med Chem Lett. 2002 May 20;12(10):1361-4. doi: 10.1016/s0960-894x(02)00191-9. Bioorg Med Chem Lett. 2002. PMID: 11992777

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