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Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, Ten Cate H, van der Poll T. Rijneveld AW, et al. Among authors: esmon ct. Blood. 2004 Mar 1;103(5):1702-9. doi: 10.1182/blood-2002-05-1380. Epub 2003 Oct 30. Blood. 2004. PMID: 14592828 Free article.
Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).
Kager LM, Schouten M, Wiersinga WJ, de Boer JD, Lattenist LC, Roelofs JJ, Meijers JC, Levi M, Dondorp AM, Esmon CT, van 't Veer C, van der Poll T. Kager LM, et al. Among authors: esmon ct. PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2306. doi: 10.1371/journal.pntd.0002306. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23875041 Free PMC article.
398 results