Nichols DE - Search Results

1

Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters.

Roman DL, Saldaña SN, Nichols DE, Carroll FI, Barker EL. Roman DL, et al. Among authors: nichols de. J Pharmacol Exp Ther. 2004 Feb;308(2):679-87. doi: 10.1124/jpet.103.057836. Epub 2003 Oct 30. J Pharmacol Exp Ther. 2004. PMID: 14593087

2

(+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity.

Oberlender R, Nichols DE. Oberlender R, et al. Among authors: nichols de. J Pharmacol Exp Ther. 1990 Dec;255(3):1098-106. J Pharmacol Exp Ther. 1990. PMID: 1979813

3

Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.

Blair JB, Kurrasch-Orbaugh D, Marona-Lewicka D, Cumbay MG, Watts VJ, Barker EL, Nichols DE. Blair JB, et al. Among authors: nichols de. J Med Chem. 2000 Nov 30;43(24):4701-10. doi: 10.1021/jm000339w. J Med Chem. 2000. PMID: 11101361

4

Serotonin 5-hydroxytryptamine 2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves.

Kurrasch-Orbaugh DM, Watts VJ, Barker EL, Nichols DE. Kurrasch-Orbaugh DM, et al. Among authors: nichols de. J Pharmacol Exp Ther. 2003 Jan;304(1):229-37. doi: 10.1124/jpet.102.042184. J Pharmacol Exp Ther. 2003. PMID: 12490596

5

Hallucinogens.

Nichols DE. Nichols DE. Pharmacol Ther. 2004 Feb;101(2):131-81. doi: 10.1016/j.pharmthera.2003.11.002. Pharmacol Ther. 2004. PMID: 14761703 Review.

6

Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists.

Braden MR, Parrish JC, Naylor JC, Nichols DE. Braden MR, et al. Among authors: nichols de. Mol Pharmacol. 2006 Dec;70(6):1956-64. doi: 10.1124/mol.106.028720. Epub 2006 Sep 25. Mol Pharmacol. 2006. PMID: 17000863

7

Engineered zinc-binding sites confirm proximity and orientation of transmembrane helices I and III in the human serotonin transporter.

White KJ, Kiser PD, Nichols DE, Barker EL. White KJ, et al. Among authors: nichols de. Protein Sci. 2006 Oct;15(10):2411-22. doi: 10.1110/ps.062386106. Protein Sci. 2006. PMID: 17008722 Free PMC article.

8

1-Methylpyridinium-4-(4-phenylmethanethiosulfonate) iodide, MTS-MPP+, a novel scanning cysteine accessibility method (SCAM) reagent for monoamine transporter studies.

Gallardo-Godoy A, Torres-Altoro MI, White KJ, Barker EL, Nichols DE. Gallardo-Godoy A, et al. Among authors: nichols de. Bioorg Med Chem. 2007 Jan 1;15(1):305-11. doi: 10.1016/j.bmc.2006.09.058. Epub 2006 Sep 29. Bioorg Med Chem. 2007. PMID: 17064910 Free PMC article.

9

Assessment of the roles of serines 5.43(239) and 5.46(242) for binding and potency of agonist ligands at the human serotonin 5-HT2A receptor.

Braden MR, Nichols DE. Braden MR, et al. Among authors: nichols de. Mol Pharmacol. 2007 Nov;72(5):1200-9. doi: 10.1124/mol.107.039255. Epub 2007 Aug 22. Mol Pharmacol. 2007. PMID: 17715398

10

Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition.

Walline CC, Nichols DE, Carroll FI, Barker EL. Walline CC, et al. Among authors: nichols de. J Pharmacol Exp Ther. 2008 Jun;325(3):791-800. doi: 10.1124/jpet.108.136200. Epub 2008 Mar 19. J Pharmacol Exp Ther. 2008. PMID: 18354055 Free PMC article.

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