Leach MO - Search Results

1

Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.

Chung YL, Troy H, Banerji U, Jackson LE, Walton MI, Stubbs M, Griffiths JR, Judson IR, Leach MO, Workman P, Ronen SM. Chung YL, et al. Among authors: leach mo. J Natl Cancer Inst. 2003 Nov 5;95(21):1624-33. doi: 10.1093/jnci/djg084. J Natl Cancer Inst. 2003. PMID: 14600095

2

Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy.

Rodrigues LM, Chung YL, Al Saffar NM, Sharp SY, Jackson LE, Banerji U, Stubbs M, Leach MO, Griffiths JR, Workman P. Rodrigues LM, et al. Among authors: leach mo. BMC Res Notes. 2012 May 23;5:250. doi: 10.1186/1756-0500-5-250. BMC Res Notes. 2012. PMID: 22621282 Free PMC article.

3

Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy.

Chung YL, Troy H, Judson IR, Leek R, Leach MO, Stubbs M, Harris AL, Griffiths JR. Chung YL, et al. Among authors: leach mo. Clin Cancer Res. 2004 Jun 1;10(11):3863-70. doi: 10.1158/1078-0432.CCR-03-0237. Clin Cancer Res. 2004. PMID: 15173095

4

Magnetic resonance spectroscopy monitoring of mitogen-activated protein kinase signaling inhibition.

Beloueche-Babari M, Jackson LE, Al-Saffar NM, Workman P, Leach MO, Ronen SM. Beloueche-Babari M, et al. Among authors: leach mo. Cancer Res. 2005 Apr 15;65(8):3356-63. doi: 10.1158/10.1158/0008-5472.CAN-03-2981. Cancer Res. 2005. PMID: 15833869

5

Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.

Al-Saffar NM, Troy H, Ramírez de Molina A, Jackson LE, Madhu B, Griffiths JR, Leach MO, Workman P, Lacal JC, Judson IR, Chung YL. Al-Saffar NM, et al. Among authors: leach mo. Cancer Res. 2006 Jan 1;66(1):427-34. doi: 10.1158/0008-5472.CAN-05-1338. Cancer Res. 2006. PMID: 16397258

6

Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts.

Chung YL, Troy H, Kristeleit R, Aherne W, Jackson LE, Atadja P, Griffiths JR, Judson IR, Workman P, Leach MO, Beloueche-Babari M. Chung YL, et al. Among authors: leach mo. Neoplasia. 2008 Apr;10(4):303-13. doi: 10.1593/neo.07834. Neoplasia. 2008. PMID: 18392140 Free PMC article.

7

Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition.

Beloueche-Babari M, Arunan V, Jackson LE, Perusinghe N, Sharp SY, Workman P, Leach MO. Beloueche-Babari M, et al. Among authors: leach mo. Oncotarget. 2010 Jul;1(3):185-97. doi: 10.18632/oncotarget.125. Oncotarget. 2010. PMID: 21037799 Free PMC article.

8

Exploiting tumor metabolism for non-invasive imaging of the therapeutic activity of molecularly targeted anticancer agents.

Beloueche-Babari M, Workman P, Leach MO. Beloueche-Babari M, et al. Among authors: leach mo. Cell Cycle. 2011 Sep 1;10(17):2883-93. doi: 10.4161/cc.10.17.17192. Epub 2011 Sep 1. Cell Cycle. 2011. PMID: 21857160 Review.

9

Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers.

Beloueche-Babari M, Arunan V, Troy H, te Poele RH, te Fong AC, Jackson LE, Payne GS, Griffiths JR, Judson IR, Workman P, Leach MO, Chung YL. Beloueche-Babari M, et al. Among authors: leach mo. Cancer Res. 2012 Feb 15;72(4):990-1000. doi: 10.1158/0008-5472.CAN-11-2688. Epub 2011 Dec 22. Cancer Res. 2012. PMID: 22194463 Free PMC article.

10

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma.

Al-Saffar NMS, Troy H, Wong Te Fong AC, Paravati R, Jackson LE, Gowan S, Boult JKR, Robinson SP, Eccles SA, Yap TA, Leach MO, Chung YL. Al-Saffar NMS, et al. Among authors: leach mo. Br J Cancer. 2018 Oct;119(9):1118-1128. doi: 10.1038/s41416-018-0242-3. Epub 2018 Oct 31. Br J Cancer. 2018. PMID: 30377337 Free PMC article.

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