Kiehn J - Search Results

1

Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing.

Thomas D, Kiehn J, Katus HA, Karle CA. Thomas D, et al. Among authors: kiehn j. Cardiovasc Res. 2003 Nov 1;60(2):235-41. doi: 10.1016/j.cardiores.2003.08.002. Cardiovasc Res. 2003. PMID: 14613852 Review.

2

Rapid component I(Kr) of the guinea-pig cardiac delayed rectifier K(+) current is inhibited by beta(1)-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways.

Karle CA, Zitron E, Zhang W, Kathöfer S, Schoels W, Kiehn J. Karle CA, et al. Among authors: kiehn j. Cardiovasc Res. 2002 Feb 1;53(2):355-62. doi: 10.1016/s0008-6363(01)00509-0. Cardiovasc Res. 2002. PMID: 11827686

3

Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line.

Wei Z, Thomas D, Karle CA, Kathöfer S, Schenkel J, Kreye VA, Ficker E, Wible BA, Kiehn J. Wei Z, et al. Among authors: kiehn j. Chin Med J (Engl). 2002 May;115(5):668-76. Chin Med J (Engl). 2002. PMID: 12133532

4

The antiarrhythmic drug BRL-32872.

Karle CA, Thomas D, Kiehn J. Karle CA, et al. Among authors: kiehn j. Cardiovasc Drug Rev. 2002 Summer;20(2):111-20. doi: 10.1111/j.1527-3466.2002.tb00186.x. Cardiovasc Drug Rev. 2002. PMID: 12177689 Review.

5

Bertosamil blocks HERG potassium channels in their open and inactivated states.

Zitron E, Karle CA, Wendt-Nordahl G, Kathöfer S, Zhang W, Thomas D, Weretka S, Kiehn J. Zitron E, et al. Among authors: kiehn j. Br J Pharmacol. 2002 Sep;137(2):221-8. doi: 10.1038/sj.bjp.0704859. Br J Pharmacol. 2002. PMID: 12208779 Free PMC article.

6

The antipsychotic drug chlorpromazine inhibits HERG potassium channels.

Thomas D, Wu K, Kathöfer S, Katus HA, Schoels W, Kiehn J, Karle CA. Thomas D, et al. Among authors: kiehn j. Br J Pharmacol. 2003 Jun;139(3):567-74. doi: 10.1038/sj.bjp.0705283. Br J Pharmacol. 2003. PMID: 12788816 Free PMC article.

7

Inhibition of cloned HERG potassium channels by the antiestrogen tamoxifen.

Thomas D, Gut B, Karsai S, Wimmer AB, Wu K, Wendt-Nordahl G, Zhang W, Kathöfer S, Schoels W, Katus HA, Kiehn J, Karle CA. Thomas D, et al. Among authors: kiehn j. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jul;368(1):41-8. doi: 10.1007/s00210-003-0766-8. Epub 2003 Jun 25. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12827215

8

Regulation of HERG potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein.

Thomas D, Zhang W, Wu K, Wimmer AB, Gut B, Wendt-Nordahl G, Kathöfer S, Kreye VA, Katus HA, Schoels W, Kiehn J, Karle CA. Thomas D, et al. Among authors: kiehn j. Cardiovasc Res. 2003 Jul 1;59(1):14-26. doi: 10.1016/s0008-6363(03)00386-9. Cardiovasc Res. 2003. PMID: 12829172

9

Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels.

Thomas D, Kathofer S, Zhang W, Wu K, Wimmer AB, Zitron E, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J. Thomas D, et al. Among authors: kiehn j. Br J Pharmacol. 2003 Nov;140(5):996-1002. doi: 10.1038/sj.bjp.0705502. Epub 2003 Sep 29. Br J Pharmacol. 2003. PMID: 14517175 Free PMC article.

10

Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.

Scholz EP, Zitron E, Kiesecker C, Lueck S, Kathöfer S, Thomas D, Weretka S, Peth S, Kreye VA, Schoels W, Katus HA, Kiehn J, Karle CA. Scholz EP, et al. Among authors: kiehn j. Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):404-14. doi: 10.1007/s00210-003-0805-5. Epub 2003 Oct 14. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14557918

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