Rosenthal PJ - Search Results

1

Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.

Pandey KC, Sijwali PS, Singh A, Na BK, Rosenthal PJ. Pandey KC, et al. Among authors: rosenthal pj. J Biol Chem. 2004 Jan 30;279(5):3484-91. doi: 10.1074/jbc.M310536200. Epub 2003 Nov 18. J Biol Chem. 2004. PMID: 14625277 Free article.

2

Folding of the Plasmodium falciparum cysteine protease falcipain-2 is mediated by a chaperone-like peptide and not the prodomain.

Sijwali PS, Shenai BR, Rosenthal PJ. Sijwali PS, et al. Among authors: rosenthal pj. J Biol Chem. 2002 Apr 26;277(17):14910-5. doi: 10.1074/jbc.M109680200. Epub 2002 Feb 4. J Biol Chem. 2002. PMID: 11827964 Free article.

3

Reducing requirements for hemoglobin hydrolysis by Plasmodium falciparum cysteine proteases.

Shenai BR, Rosenthal PJ. Shenai BR, et al. Among authors: rosenthal pj. Mol Biochem Parasitol. 2002 Jun;122(1):99-104. doi: 10.1016/s0166-6851(02)00075-0. Mol Biochem Parasitol. 2002. PMID: 12076775 No abstract available.

4

Stage-specific antimalarial activity of cysteine protease inhibitors.

Shenai BR, Semenov AV, Rosenthal PJ. Shenai BR, et al. Among authors: rosenthal pj. Biol Chem. 2002 May;383(5):843-7. doi: 10.1515/BC.2002.089. Biol Chem. 2002. PMID: 12108550

5

Cysteine proteases of malaria parasites: targets for chemotherapy.

Rosenthal PJ, Sijwali PS, Singh A, Shenai BR. Rosenthal PJ, et al. Curr Pharm Des. 2002;8(18):1659-72. doi: 10.2174/1381612023394197. Curr Pharm Des. 2002. PMID: 12132997 Review.

6

Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites.

Singh A, Shenai BR, Choe Y, Gut J, Sijwali PS, Craik CS, Rosenthal PJ. Singh A, et al. Among authors: rosenthal pj. Biochem J. 2002 Nov 15;368(Pt 1):273-81. doi: 10.1042/BJ20020753. Biochem J. 2002. PMID: 12169096 Free PMC article.

7

Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones.

Shenai BR, Lee BJ, Alvarez-Hernandez A, Chong PY, Emal CD, Neitz RJ, Roush WR, Rosenthal PJ. Shenai BR, et al. Among authors: rosenthal pj. Antimicrob Agents Chemother. 2003 Jan;47(1):154-60. doi: 10.1128/AAC.47.1.154-160.2003. Antimicrob Agents Chemother. 2003. PMID: 12499184 Free PMC article.

8

Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines.

Batra S, Sabnis YA, Rosenthal PJ, Avery MA. Batra S, et al. Among authors: rosenthal pj. Bioorg Med Chem. 2003 May 15;11(10):2293-9. doi: 10.1016/s0968-0896(03)00117-2. Bioorg Med Chem. 2003. PMID: 12713840

9

Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax.

Na BK, Shenai BR, Sijwali PS, Choe Y, Pandey KC, Singh A, Craik CS, Rosenthal PJ. Na BK, et al. Among authors: rosenthal pj. Biochem J. 2004 Mar 1;378(Pt 2):529-38. doi: 10.1042/BJ20031487. Biochem J. 2004. PMID: 14629194 Free PMC article.

10

Antimalarial activities of novel synthetic cysteine protease inhibitors.

Lee BJ, Singh A, Chiang P, Kemp SJ, Goldman EA, Weinhouse MI, Vlasuk GP, Rosenthal PJ. Lee BJ, et al. Among authors: rosenthal pj. Antimicrob Agents Chemother. 2003 Dec;47(12):3810-4. doi: 10.1128/AAC.47.12.3810-3814.2003. Antimicrob Agents Chemother. 2003. PMID: 14638488 Free PMC article.

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