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NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function.
Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K. Kuwahara K, et al. Among authors: arai y. EMBO J. 2003 Dec 1;22(23):6310-21. doi: 10.1093/emboj/cdg601. EMBO J. 2003. PMID: 14633990 Free PMC article.
Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death.
Yasuno S, Usami S, Kuwahara K, Nakanishi M, Arai Y, Kinoshita H, Nakagawa Y, Fujiwara M, Murakami M, Ueshima K, Harada M, Nakao K. Yasuno S, et al. Among authors: arai y. Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1804-10. doi: 10.1152/ajpheart.01033.2008. Epub 2009 Apr 3. Am J Physiol Heart Circ Physiol. 2009. PMID: 19346456 Free article.
T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
Kinoshita H, Kuwahara K, Takano M, Arai Y, Kuwabara Y, Yasuno S, Nakagawa Y, Nakanishi M, Harada M, Fujiwara M, Murakami M, Ueshima K, Nakao K. Kinoshita H, et al. Among authors: arai y. Circulation. 2009 Sep 1;120(9):743-52. doi: 10.1161/CIRCULATIONAHA.109.857011. Epub 2009 Aug 17. Circulation. 2009. PMID: 19687356
Increased expression of HCN channels in the ventricular myocardium contributes to enhanced arrhythmicity in mouse failing hearts.
Kuwabara Y, Kuwahara K, Takano M, Kinoshita H, Arai Y, Yasuno S, Nakagawa Y, Igata S, Usami S, Minami T, Yamada Y, Nakao K, Yamada C, Shibata J, Nishikimi T, Ueshima K, Nakao K. Kuwabara Y, et al. Among authors: arai y. J Am Heart Assoc. 2013 May 24;2(3):e000150. doi: 10.1161/JAHA.113.000150. J Am Heart Assoc. 2013. PMID: 23709563 Free PMC article.
Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure.
Yamada Y, Kinoshita H, Kuwahara K, Nakagawa Y, Kuwabara Y, Minami T, Yamada C, Shibata J, Nakao K, Cho K, Arai Y, Yasuno S, Nishikimi T, Ueshima K, Kamakura S, Nishida M, Kiyonaka S, Mori Y, Kimura T, Kangawa K, Nakao K. Yamada Y, et al. Among authors: arai y. Cardiovasc Res. 2014 Oct 1;104(1):183-93. doi: 10.1093/cvr/cvu185. Epub 2014 Aug 5. Cardiovasc Res. 2014. PMID: 25100767 Free article.
The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy.
Yamada C, Kuwahara K, Yamazaki M, Nakagawa Y, Nishikimi T, Kinoshita H, Kuwabara Y, Minami T, Yamada Y, Shibata J, Nakao K, Cho K, Arai Y, Honjo H, Kamiya K, Nakao K, Kimura T. Yamada C, et al. Among authors: arai y. Cardiovasc Res. 2016 Jan 1;109(1):162-73. doi: 10.1093/cvr/cvv248. Epub 2015 Nov 3. Cardiovasc Res. 2016. PMID: 26531129 Free article.
Podocyte-specific expression of tamoxifen-inducible Cre recombinase in mice.
Yokoi H, Kasahara M, Mukoyama M, Mori K, Kuwahara K, Fujikura J, Arai Y, Saito Y, Ogawa Y, Kuwabara T, Sugawara A, Nakao K. Yokoi H, et al. Among authors: arai y. Nephrol Dial Transplant. 2010 Jul;25(7):2120-4. doi: 10.1093/ndt/gfq029. Epub 2010 Feb 11. Nephrol Dial Transplant. 2010. PMID: 20150167
Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart.
Otani K, Tokudome T, Kamiya CA, Mao Y, Nishimura H, Hasegawa T, Arai Y, Kaneko M, Shioi G, Ishida J, Fukamizu A, Osaki T, Nagai-Okatani C, Minamino N, Ensho T, Hino J, Murata S, Takegami M, Nishimura K, Kishimoto I, Miyazato M, Harada-Shiba M, Yoshimatsu J, Nakao K, Ikeda T, Kangawa K. Otani K, et al. Among authors: arai y. Circulation. 2020 Feb 18;141(7):571-588. doi: 10.1161/CIRCULATIONAHA.119.039761. Epub 2019 Oct 31. Circulation. 2020. PMID: 31665900
4,193 results