Kuntz DA - Search Results

1

Comparison of kifunensine and 1-deoxymannojirimycin binding to class I and II alpha-mannosidases demonstrates different saccharide distortions in inverting and retaining catalytic mechanisms.

Shah N, Kuntz DA, Rose DR. Shah N, et al. Among authors: kuntz da. Biochemistry. 2003 Dec 2;42(47):13812-6. doi: 10.1021/bi034742r. Biochemistry. 2003. PMID: 14636047

2

A single chain Fv fragment of P-glycoprotein-specific monoclonal antibody C219. Design, expression, and crystal structure at 2.4 A resolution.

Hoedemaeker FJ, Signorelli T, Johns K, Kuntz DA, Rose DR. Hoedemaeker FJ, et al. Among authors: kuntz da. J Biol Chem. 1997 Nov 21;272(47):29784-9. doi: 10.1074/jbc.272.47.29784. J Biol Chem. 1997. PMID: 9368049 Free article.

3

The Drosophila GMII gene encodes a Golgi alpha-mannosidase II.

Rabouille C, Kuntz DA, Lockyer A, Watson R, Signorelli T, Rose DR, van den Heuvel M, Roberts DB. Rabouille C, et al. Among authors: kuntz da. J Cell Sci. 1999 Oct;112 ( Pt 19):3319-30. doi: 10.1242/jcs.112.19.3319. J Cell Sci. 1999. PMID: 10504337

4

Antibody C219 recognizes an alpha-helical epitope on P-glycoprotein.

van Den Elsen JM, Kuntz DA, Hoedemaeker FJ, Rose DR. van Den Elsen JM, et al. Among authors: kuntz da. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13679-84. doi: 10.1073/pnas.96.24.13679. Proc Natl Acad Sci U S A. 1999. PMID: 10570132 Free PMC article.

5

Overcoming multi-drug resistance using an intracellular anti-MDR1 sFv.

Heike Y, Kasono K, Kunisaki C, Hama S, Saijo N, Tsuruo T, Kuntz DA, Rose DR, Curiel DT. Heike Y, et al. Among authors: kuntz da. Int J Cancer. 2001 Apr 1;92(1):115-22. Int J Cancer. 2001. PMID: 11279614

6

Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.

van den Elsen JM, Kuntz DA, Rose DR. van den Elsen JM, et al. Among authors: kuntz da. EMBO J. 2001 Jun 15;20(12):3008-17. doi: 10.1093/emboj/20.12.3008. EMBO J. 2001. PMID: 11406577 Free PMC article.

7

Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates.

Numao S, Kuntz DA, Withers SG, Rose DR. Numao S, et al. Among authors: kuntz da. J Biol Chem. 2003 Nov 28;278(48):48074-83. doi: 10.1074/jbc.M309249200. Epub 2003 Sep 5. J Biol Chem. 2003. PMID: 12960159 Free article.

8

A combined STD-NMR/molecular modeling protocol for predicting the binding modes of the glycosidase inhibitors kifunensine and salacinol to Golgi alpha-mannosidase II.

Wen X, Yuan Y, Kuntz DA, Rose DR, Pinto BM. Wen X, et al. Among authors: kuntz da. Biochemistry. 2005 May 10;44(18):6729-37. doi: 10.1021/bi0500426. Biochemistry. 2005. PMID: 15865418

9

Expression and purification of sea raven type II antifreeze protein from Drosophila melanogaster S2 cells.

Scotter AJ, Kuntz DA, Saul M, Graham LA, Davies PL, Rose DR. Scotter AJ, et al. Among authors: kuntz da. Protein Expr Purif. 2006 Jun;47(2):374-83. doi: 10.1016/j.pep.2005.10.028. Epub 2005 Nov 21. Protein Expr Purif. 2006. PMID: 16330225

10

Structural basis of the inhibition of Golgi alpha-mannosidase II by mannostatin A and the role of the thiomethyl moiety in ligand-protein interactions.

Kawatkar SP, Kuntz DA, Woods RJ, Rose DR, Boons GJ. Kawatkar SP, et al. Among authors: kuntz da. J Am Chem Soc. 2006 Jun 28;128(25):8310-9. doi: 10.1021/ja061216p. J Am Chem Soc. 2006. PMID: 16787095 Free PMC article.

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