Chalmers DT - Search Results

1

Ligand specific up-regulation of a Renilla reniformis luciferase-tagged, structurally unstable muscarinic M3 chimeric G protein-coupled receptor.

Zeng FY, McLean AJ, Milligan G, Lerner M, Chalmers DT, Behan DP. Zeng FY, et al. Among authors: chalmers dt. Mol Pharmacol. 2003 Dec;64(6):1474-84. doi: 10.1124/mol.64.6.1474. Mol Pharmacol. 2003. PMID: 14645678

2

Constitutively activated G protein-coupled receptors: a novel approach to CNS drug discovery.

Menzaghi F, Behan DP, Chalmers DT. Menzaghi F, et al. Among authors: chalmers dt. Curr Drug Targets CNS Neurol Disord. 2002 Feb;1(1):105-21. doi: 10.2174/1568007023339508. Curr Drug Targets CNS Neurol Disord. 2002. PMID: 12769637 Review.

3

The use of constitutively active receptors for drug discovery at the G protein-coupled receptor gene pool.

Behan DP, Chalmers DT. Behan DP, et al. Among authors: chalmers dt. Curr Opin Drug Discov Devel. 2001 Sep;4(5):548-60. Curr Opin Drug Discov Devel. 2001. PMID: 12825451 Review.

4

The use of constitutively active GPCRs in drug discovery and functional genomics.

Chalmers DT, Behan DP. Chalmers DT, et al. Nat Rev Drug Discov. 2002 Aug;1(8):599-608. doi: 10.1038/nrd872. Nat Rev Drug Discov. 2002. PMID: 12402500 Review.

5

Global analysis of G-protein-coupled receptor signaling in human tissues.

Hakak Y, Shrestha D, Goegel MC, Behan DP, Chalmers DT. Hakak Y, et al. Among authors: chalmers dt. FEBS Lett. 2003 Aug 28;550(1-3):11-7. doi: 10.1016/s0014-5793(03)00762-2. FEBS Lett. 2003. PMID: 12935878 Free article.

6

Neurotransmission- and cellular stress-related gene expression associated with prepulse inhibition in mice.

Grottick AJ, Bagnol D, Phillips S, McDonald J, Behan DP, Chalmers DT, Hakak Y. Grottick AJ, et al. Among authors: chalmers dt. Brain Res Mol Brain Res. 2005 Sep 13;139(1):153-62. doi: 10.1016/j.molbrainres.2005.05.020. Brain Res Mol Brain Res. 2005. PMID: 15961183

7

Generation and analysis of constitutively active and physically destabilized mutants of the human beta(1)-adrenoceptor.

McLean AJ, Zeng FY, Behan D, Chalmers D, Milligan G. McLean AJ, et al. Mol Pharmacol. 2002 Sep;62(3):747-55. doi: 10.1124/mol.62.3.747. Mol Pharmacol. 2002. PMID: 12181453

8

Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization.

Thomsen WJ, Grottick AJ, Menzaghi F, Reyes-Saldana H, Espitia S, Yuskin D, Whelan K, Martin M, Morgan M, Chen W, Al-Shamma H, Smith B, Chalmers D, Behan D. Thomsen WJ, et al. J Pharmacol Exp Ther. 2008 May;325(2):577-87. doi: 10.1124/jpet.107.133348. Epub 2008 Feb 5. J Pharmacol Exp Ther. 2008. PMID: 18252809

9

Neurobiology of corticotropin releasing factor (CRF) receptors and CRF-binding protein: implications for the treatment of CNS disorders.

Behan DP, Grigoriadis DE, Lovenberg T, Chalmers D, Heinrichs S, Liaw C, De Souza EB. Behan DP, et al. Mol Psychiatry. 1996 Sep;1(4):265-77. Mol Psychiatry. 1996. PMID: 9118350 Review.

10

Corticotropin releasing factor binding protein (CRF-BP) is expressed in neuronal and astrocytic cells.

Behan DP, Maciejewski D, Chalmers D, De Souza EB. Behan DP, et al. Brain Res. 1995 Nov 6;698(1-2):259-64. doi: 10.1016/0006-8993(95)01014-m. Brain Res. 1995. PMID: 8581494

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