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S-prenylated cysteine analogues inhibit receptor-mediated G protein activation in native human granulocyte and reconstituted bovine retinal rod outer segment membranes.
Scheer A, Gierschik P. Scheer A, et al. Biochemistry. 1995 Apr 18;34(15):4952-61. doi: 10.1021/bi00015a006. Biochemistry. 1995. PMID: 7711017
We have previously shown that the S-prenylated cysteine analogue N-acetyl-S-trans,trans-farnesyl-L-cysteine (L-AFC) inhibits basal and formyl peptide receptor-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) (GTP[S]) to and hydrolysis of GTP by membranes of HL-60 granulo …
We have previously shown that the S-prenylated cysteine analogue N-acetyl-S-trans,trans-farnesyl-L-cysteine (L-AFC) inhibits basal and formy …
Cellular imaging in drug discovery.
Lang P, Yeow K, Nichols A, Scheer A. Lang P, et al. Among authors: scheer a. Nat Rev Drug Discov. 2006 Apr;5(4):343-56. doi: 10.1038/nrd2008. Nat Rev Drug Discov. 2006. PMID: 16582878 Review.
224 results