Siraganian RP - Search Results

1

Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.

Suzuki-Inoue K, Wilde JI, Andrews RK, Auger JM, Siraganian RP, Sekiya F, Rhee SG, Watson SP. Suzuki-Inoue K, et al. Among authors: siraganian rp. Biochem J. 2004 Mar 15;378(Pt 3):1023-9. doi: 10.1042/BJ20031430. Biochem J. 2004. PMID: 14656219 Free PMC article.

2

Fc epsilon RI aggregation induces tyrosine phosphorylation of a novel 72 kDa protein downstream of Syk.

Hamawy MM, Fischler C, Zhang J, Siraganian RP. Hamawy MM, et al. Among authors: siraganian rp. Biochem Biophys Res Commun. 1997 Oct 29;239(3):670-5. doi: 10.1006/bbrc.1997.7532. Biochem Biophys Res Commun. 1997. PMID: 9367826

3

Protein tyrosine kinase Syk in mast cell signaling.

Siraganian RP, Zhang J, Suzuki K, Sada K. Siraganian RP, et al. Mol Immunol. 2002 Sep;38(16-18):1229-33. doi: 10.1016/s0161-5890(02)00068-8. Mol Immunol. 2002. PMID: 12217388 Review.

4

Activation of protein-tyrosine kinase Pyk2 is downstream of Syk in FcepsilonRI signaling.

Okazaki H, Zhang J, Hamawy MM, Siraganian RP. Okazaki H, et al. Among authors: siraganian rp. J Biol Chem. 1997 Dec 19;272(51):32443-7. doi: 10.1074/jbc.272.51.32443. J Biol Chem. 1997. PMID: 9405454 Free article.

5

Regulation of protein kinase CbetaI by two protein-tyrosine kinases, Btk and Syk.

Kawakami Y, Kitaura J, Hartman SE, Lowell CA, Siraganian RP, Kawakami T. Kawakami Y, et al. Among authors: siraganian rp. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7423-8. doi: 10.1073/pnas.120175097. Proc Natl Acad Sci U S A. 2000. PMID: 10852954 Free PMC article.

6

Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.

Paolini R, Molfetta R, Beitz LO, Zhang J, Scharenberg AM, Piccoli M, Frati L, Siraganian R, Santoni A. Paolini R, et al. J Biol Chem. 2002 Oct 4;277(40):36940-7. doi: 10.1074/jbc.M204948200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145291 Free article.

7

Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides.

Kimura T, Sakamoto H, Appella E, Siraganian RP. Kimura T, et al. Among authors: siraganian rp. Mol Cell Biol. 1996 Apr;16(4):1471-8. doi: 10.1128/MCB.16.4.1471. Mol Cell Biol. 1996. PMID: 8657120 Free PMC article.

8

Tyrosines in the carboxyl terminus regulate Syk kinase activity and function.

de Castro RO, Zhang J, Jamur MC, Oliver C, Siraganian RP. de Castro RO, et al. Among authors: siraganian rp. J Biol Chem. 2010 Aug 20;285(34):26674-84. doi: 10.1074/jbc.M110.134262. Epub 2010 Jun 16. J Biol Chem. 2010. PMID: 20554527 Free PMC article.

9

Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody.

Zhang J, Billingsley ML, Kincaid RL, Siraganian RP. Zhang J, et al. Among authors: siraganian rp. J Biol Chem. 2000 Nov 10;275(45):35442-7. doi: 10.1074/jbc.M004549200. J Biol Chem. 2000. PMID: 10931839 Free article.

10

Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity.

Zhang J, Kimura T, Siraganian RP. Zhang J, et al. Among authors: siraganian rp. J Immunol. 1998 Oct 15;161(8):4366-74. J Immunol. 1998. PMID: 9780214

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