Sadler PJ - Search Results

1

Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers.

Chen H, Parkinson JA, Nováková O, Bella J, Wang F, Dawson A, Gould R, Parsons S, Brabec V, Sadler PJ. Chen H, et al. Among authors: sadler pj. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14623-8. doi: 10.1073/pnas.2434016100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657383 Free PMC article.

2

Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts.

Chen H, Parkinson JA, Parsons S, Coxall RA, Gould RO, Sadler PJ. Chen H, et al. Among authors: sadler pj. J Am Chem Soc. 2002 Mar 27;124(12):3064-82. doi: 10.1021/ja017482e. J Am Chem Soc. 2002. PMID: 11902898

3

Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.

Chen H, Parkinson JA, Morris RE, Sadler PJ. Chen H, et al. Among authors: sadler pj. J Am Chem Soc. 2003 Jan 8;125(1):173-86. doi: 10.1021/ja027719m. J Am Chem Soc. 2003. PMID: 12515520

4

Kinetics of aquation and anation of ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts.

Wang F, Chen H, Parsons S, Oswald ID, Davidson JE, Sadler PJ. Wang F, et al. Among authors: sadler pj. Chemistry. 2003 Dec 5;9(23):5810-20. doi: 10.1002/chem.200304724. Chemistry. 2003. PMID: 14673852

5

Protein recognition of macrocycles: binding of anti-HIV metallocyclams to lysozyme.

Hunter TM, McNae IW, Liang X, Bella J, Parsons S, Walkinshaw MD, Sadler PJ. Hunter TM, et al. Among authors: sadler pj. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2288-92. doi: 10.1073/pnas.0407595102. Epub 2005 Feb 8. Proc Natl Acad Sci U S A. 2005. PMID: 15701702 Free PMC article.

6

Controlling ligand substitution reactions of organometallic complexes: tuning cancer cell cytotoxicity.

Wang F, Habtemariam A, van der Geer EP, Fernández R, Melchart M, Deeth RJ, Aird R, Guichard S, Fabbiani FP, Lozano-Casal P, Oswald ID, Jodrell DI, Parsons S, Sadler PJ. Wang F, et al. Among authors: sadler pj. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18269-74. doi: 10.1073/pnas.0505798102. Epub 2005 Dec 13. Proc Natl Acad Sci U S A. 2005. PMID: 16352726 Free PMC article.

7

Ruthenation of duplex and single-stranded d(CGGCCG) by organometallic anticancer complexes.

Liu HK, Wang F, Parkinson JA, Bella J, Sadler PJ. Liu HK, et al. Among authors: sadler pj. Chemistry. 2006 Aug 7;12(23):6151-65. doi: 10.1002/chem.200600110. Chemistry. 2006. PMID: 16807967

8

Bifunctional amine-tethered ruthenium(II) arene complexes form monofunctional adducts on DNA.

Melchart M, Habtemariam A, Novakova O, Moggach SA, Fabbiani FP, Parsons S, Brabec V, Sadler PJ. Melchart M, et al. Among authors: sadler pj. Inorg Chem. 2007 Oct 15;46(21):8950-62. doi: 10.1021/ic700799w. Epub 2007 Sep 13. Inorg Chem. 2007. PMID: 17850143

9

A potent cytotoxic photoactivated platinum complex.

Mackay FS, Woods JA, Heringová P, Kaspárková J, Pizarro AM, Moggach SA, Parsons S, Brabec V, Sadler PJ. Mackay FS, et al. Among authors: sadler pj. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20743-8. doi: 10.1073/pnas.0707742105. Epub 2007 Dec 19. Proc Natl Acad Sci U S A. 2007. PMID: 18093923 Free PMC article.

10

Catalytic organometallic anticancer complexes.

Dougan SJ, Habtemariam A, McHale SE, Parsons S, Sadler PJ. Dougan SJ, et al. Among authors: sadler pj. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11628-33. doi: 10.1073/pnas.0800076105. Epub 2008 Aug 7. Proc Natl Acad Sci U S A. 2008. PMID: 18687892 Free PMC article.

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