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Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication.
Kudoh A, Daikoku T, Sugaya Y, Isomura H, Fujita M, Kiyono T, Nishiyama Y, Tsurumi T. Kudoh A, et al. Among authors: tsurumi t. J Virol. 2004 Jan;78(1):104-15. doi: 10.1128/jvi.78.1.104-115.2004. J Virol. 2004. PMID: 14671092 Free PMC article.
The induction of lytic replication of the Epstein-Barr virus (EBV) completely arrests cell cycle progression, in spite of elevation of S-phase cyclin-dependent kinase (CDK) activity, thereby causing accumulation of hyperphosphorylated forms of retinoblastoma (Rb) protein (A. Kudo …
The induction of lytic replication of the Epstein-Barr virus (EBV) completely arrests cell cycle progression, in spite of elevation of S-pha …
Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication.
Isomura H, Stinski MF, Kudoh A, Daikoku T, Shirata N, Tsurumi T. Isomura H, et al. Among authors: tsurumi t. J Virol. 2005 Aug;79(15):9597-607. doi: 10.1128/JVI.79.15.9597-9607.2005. J Virol. 2005. PMID: 16014922 Free PMC article.
We previously demonstrated that the major immediate early (MIE) proximal enhancer containing one GC box and the TATA box containing promoter are minimal elements required for transcription and viral replication in human fibroblast cells (H. Isomura, T. Tsurumi, M. F …
We previously demonstrated that the major immediate early (MIE) proximal enhancer containing one GC box and the TATA box containing promoter …
196 results