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Pilot trial evaluating an 123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer.
Wong JY, Chu DZ, Williams LE, Yamauchi DM, Ikle DN, Kwok CS, Liu A, Wilczynski S, Colcher D, Yazaki PJ, Shively JE, Wu AM, Raubitschek AA. Wong JY, et al. Among authors: williams le. Clin Cancer Res. 2004 Aug 1;10(15):5014-21. doi: 10.1158/1078-0432.CCR-03-0576. Clin Cancer Res. 2004. PMID: 15297402 Clinical Trial.
Humanization of the anti-CEA T84.66 antibody based on crystal structure data.
Yazaki PJ, Sherman MA, Shively JE, Ikle D, Williams LE, Wong JY, Colcher D, Wu AM, Raubitschek AA. Yazaki PJ, et al. Among authors: williams le. Protein Eng Des Sel. 2004 May;17(5):481-9. doi: 10.1093/protein/gzh056. Epub 2004 Aug 17. Protein Eng Des Sel. 2004. PMID: 15316127
Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.
Kenanova V, Olafsen T, Crow DM, Sundaresan G, Subbarayan M, Carter NH, Ikle DN, Yazaki PJ, Chatziioannou AF, Gambhir SS, Williams LE, Shively JE, Colcher D, Raubitschek AA, Wu AM. Kenanova V, et al. Among authors: williams le. Cancer Res. 2005 Jan 15;65(2):622-31. Cancer Res. 2005. PMID: 15695407 Free PMC article.
A pretherapy biodistribution and dosimetry study of indium-111-radiolabeled trastuzumab in patients with human epidermal growth factor receptor 2-overexpressing breast cancer.
Wong JY, Raubitschek A, Yamauchi D, Williams LE, Wu AM, Yazaki P, Shively JE, Colcher D, Somlo G. Wong JY, et al. Among authors: williams le. Cancer Biother Radiopharm. 2010 Aug;25(4):387-94. doi: 10.1089/cbr.2010.0783. Cancer Biother Radiopharm. 2010. PMID: 20707718 Free PMC article.
Phase I/II Trial of Anticarcinoembryonic Antigen Radioimmunotherapy, Gemcitabine, and Hepatic Arterial Infusion of Fluorodeoxyuridine Postresection of Liver Metastasis for Colorectal Carcinoma.
Cahan B, Leong L, Wagman L, Yamauchi D, Shibata S, Wilzcynski S, Williams LE, Yazaki P, Colcher D, Frankel P, Wu A, Raubitschek A, Shively J, Wong JYC. Cahan B, et al. Among authors: williams le. Cancer Biother Radiopharm. 2017 Sep;32(7):258-265. doi: 10.1089/cbr.2017.2223. Cancer Biother Radiopharm. 2017. PMID: 28910150 Free PMC article. Clinical Trial.
410 results