Rowley MJ - Search Results

1

A diabetes-related epitope of GAD65: a major diabetes-related conformational epitope on GAD65.

Myers MA, Fenalti G, Gray R, Scealy M, Tong JC, El-Kabbani O, Rowley MJ. Myers MA, et al. Among authors: rowley mj. Ann N Y Acad Sci. 2003 Nov;1005:250-2. doi: 10.1196/annals.1288.037. Ann N Y Acad Sci. 2003. PMID: 14679070

2

The PEVKEK region of the pyridoxal phosphate binding domain of GAD65 expresses a dominant B cell epitope for type 1 diabetes sera.

Tong JC, Myers MA, Mackay IR, Zimmet PZ, Rowley MJ. Tong JC, et al. Among authors: rowley mj. Ann N Y Acad Sci. 2002 Apr;958:182-9. doi: 10.1111/j.1749-6632.2002.tb02966.x. Ann N Y Acad Sci. 2002. PMID: 12021103

3

Amino acids critical for binding of autoantibody to an immunodominant conformational epitope of the pyruvate dehydrogenase complex subunit E2: identification by phage display and site-directed mutagenesis.

Scealy M, Mackay IR, Rowley MJ. Scealy M, et al. Among authors: rowley mj. Mol Immunol. 2006 Feb;43(6):745-53. doi: 10.1016/j.molimm.2005.03.011. Epub 2005 Apr 18. Mol Immunol. 2006. PMID: 16360019

4

Characterisation of an autoreactive conformational epitope on GAD65 recognised by the human monoclonal antibody b78 using a combination of phage display, in vitro mutagenesis and molecular modelling.

O'Connor KH, Banga JP, Darmanin C, El-Kabbani O, Mackay IR, Rowley MJ. O'Connor KH, et al. Among authors: rowley mj. J Autoimmun. 2006 May;26(3):172-81. doi: 10.1016/j.jaut.2006.02.001. Epub 2006 Mar 24. J Autoimmun. 2006. PMID: 16564157

5

Molecular characterization of a disease associated conformational epitope on GAD65 recognised by a human monoclonal antibody b96.11.

Fenalti G, Hampe CS, O'connor K, Banga JP, Mackay IR, Rowley MJ, El-Kabbani O. Fenalti G, et al. Among authors: rowley mj. Mol Immunol. 2007 Feb;44(6):1178-89. doi: 10.1016/j.molimm.2006.06.025. Epub 2006 Aug 22. Mol Immunol. 2007. PMID: 16930708

6

COOH-terminal clustering of autoantibody and T-cell determinants on the structure of GAD65 provide insights into the molecular basis of autoreactivity.

Fenalti G, Hampe CS, Arafat Y, Law RH, Banga JP, Mackay IR, Whisstock JC, Buckle AM, Rowley MJ. Fenalti G, et al. Among authors: rowley mj. Diabetes. 2008 May;57(5):1293-301. doi: 10.2337/db07-1461. Epub 2008 Jan 9. Diabetes. 2008. PMID: 18184926

7

GAD65 as a prototypic autoantigen.

Fenalti G, Rowley MJ. Fenalti G, et al. Among authors: rowley mj. J Autoimmun. 2008 Nov;31(3):228-32. doi: 10.1016/j.jaut.2008.04.013. Epub 2008 Jun 2. J Autoimmun. 2008. PMID: 18514483

8

Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling.

Myers MA, Davies JM, Tong JC, Whisstock J, Scealy M, Mackay IR, Rowley MJ. Myers MA, et al. Among authors: rowley mj. J Immunol. 2000 Oct 1;165(7):3830-8. doi: 10.4049/jimmunol.165.7.3830. J Immunol. 2000. PMID: 11034389

9

Enzymatic characterization of a recombinant isoform hybrid of glutamic acid decarboxylase (rGAD67/65) expressed in yeast.

Tong JC, Mackay IR, Chin J, Law RH, Fayad K, Rowley MJ. Tong JC, et al. Among authors: rowley mj. J Biotechnol. 2002 Aug 7;97(2):183-90. doi: 10.1016/s0168-1656(02)00060-3. J Biotechnol. 2002. PMID: 12067524

10

Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry.

Xu Y, Ramsland PA, Davies JM, Scealy M, Nandakumar KS, Holmdahl R, Rowley MJ. Xu Y, et al. Among authors: rowley mj. Mol Immunol. 2004 Jun;41(4):411-9. doi: 10.1016/j.molimm.2004.03.025. Mol Immunol. 2004. PMID: 15163538

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