Owa T - Search Results

1

Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.

Abbate F, Casini A, Owa T, Scozzafava A, Supuran CT. Abbate F, et al. Among authors: owa t. Bioorg Med Chem Lett. 2004 Jan 5;14(1):217-23. doi: 10.1016/j.bmcl.2003.09.062. Bioorg Med Chem Lett. 2004. PMID: 14684331

2

Anticancer and antiviral sulfonamides.

Scozzafava A, Owa T, Mastrolorenzo A, Supuran CT. Scozzafava A, et al. Among authors: owa t. Curr Med Chem. 2003 Jun;10(11):925-53. doi: 10.2174/0929867033457647. Curr Med Chem. 2003. PMID: 12678681 Review.

3

Sulfonamide drugs binding to the colchicine site of tubulin: thermodynamic analysis of the drug-tubulin interactions by isothermal titration calorimetry.

Banerjee M, Poddar A, Mitra G, Surolia A, Owa T, Bhattacharyya B. Banerjee M, et al. Among authors: owa t. J Med Chem. 2005 Jan 27;48(2):547-55. doi: 10.1021/jm0494974. J Med Chem. 2005. PMID: 15658868

4

Synthesis and biological evaluation of N-(7-indolyl)-3-pyridinesulfonamide derivatives as potent antitumor agents.

Owa T, Yoshino H, Okauchi T, Okabe T, Ozawa Y, Hata Sugi N, Yoshimatsu K, Nagasu T, Koyanagi N, Kitoh K. Owa T, et al. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2097-100. doi: 10.1016/s0960-894x(02)00376-1. Bioorg Med Chem Lett. 2002. PMID: 12127512

5

Discovery of novel antitumor sulfonamides targeting G1 phase of the cell cycle.

Owa T, Yoshino H, Okauchi T, Yoshimatsu K, Ozawa Y, Sugi NH, Nagasu T, Koyanagi N, Kitoh K. Owa T, et al. J Med Chem. 1999 Sep 23;42(19):3789-99. doi: 10.1021/jm9902638. J Med Chem. 1999. PMID: 10508428

6

A focused compound library of novel N-(7-indolyl)benzenesulfonamides for the discovery of potent cell cycle inhibitors.

Owa T, Okauchi T, Yoshimatsu K, Sugi NH, Ozawa Y, Nagasu T, Koyanagi N, Okabe T, Kitoh K, Yoshino H. Owa T, et al. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1223-6. doi: 10.1016/s0960-894x(00)00219-5. Bioorg Med Chem Lett. 2000. PMID: 10866386

7

Array-based structure and gene expression relationship study of antitumor sulfonamides including N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide and N-(3-chloro-7-indolyl)-1,4-benzenedisulfonamide.

Owa T, Yokoi A, Yamazaki K, Yoshimatsu K, Yamori T, Nagasu T. Owa T, et al. J Med Chem. 2002 Oct 24;45(22):4913-22. doi: 10.1021/jm0201060. J Med Chem. 2002. PMID: 12383017

8

Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents.

Owa T, Yoshino H, Yoshimatsu K, Nagasu T. Owa T, et al. Curr Med Chem. 2001 Oct;8(12):1487-503. doi: 10.2174/0929867013371996. Curr Med Chem. 2001. PMID: 11562278 Review.

9

Therapeutic potential and molecular mechanism of a novel sulfonamide anticancer drug, indisulam (E7070) in combination with CPT-11 for cancer treatment.

Ozawa Y, Kusano K, Owa T, Yokoi A, Asada M, Yoshimatsu K. Ozawa Y, et al. Among authors: owa t. Cancer Chemother Pharmacol. 2012 May;69(5):1353-62. doi: 10.1007/s00280-012-1844-8. Epub 2012 Feb 17. Cancer Chemother Pharmacol. 2012. PMID: 22349812

10

E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo.

Ozawa Y, Sugi NH, Nagasu T, Owa T, Watanabe T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K. Ozawa Y, et al. Among authors: owa t. Eur J Cancer. 2001 Nov;37(17):2275-82. doi: 10.1016/s0959-8049(01)00275-1. Eur J Cancer. 2001. PMID: 11677118

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