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Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators.
Kitagawa DAS, Rodrigues RB, Silva TN, Dos Santos WV, da Rocha VCV, de Almeida JSFD, Bernardo LB, Carvalho-Silva T, Ferreira CN, da Silva AAT, Simas ABC, Nepovimova E, Kuča K, França TCC, Cavalcante SFA. Kitagawa DAS, et al. Among authors: simas abc. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1370-1377. doi: 10.1080/14756366.2021.1916009. J Enzyme Inhib Med Chem. 2021. PMID: 34148470 Free PMC article.
Synthesis and in vitro evaluation of neutral aryloximes as reactivators of Electrophorus eel acetylcholinesterase inhibited by NEMP, a VX surrogate.
Cavalcante SFA, Kitagawa DAS, Rodrigues RB, Bernardo LB, da Silva TN, Dos Santos WV, Correa ABA, de Almeida JSFD, França TCC, Kuča K, Simas ABC. Cavalcante SFA, et al. Among authors: simas abc. Chem Biol Interact. 2019 Aug 25;309:108682. doi: 10.1016/j.cbi.2019.05.048. Epub 2019 Jun 1. Chem Biol Interact. 2019. PMID: 31163137
In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon.
Kitagawa DAS, Cavalcante SFA, de Paula RL, Rodrigues RB, Bernardo LB, da Silva MCJ, da Silva TN, Dos Santos WV, Granjeiro JM, de Almeida JSFD, Barcellos MC, de A Correa AB, França TCC, Kuča K, Simas ABC. Kitagawa DAS, et al. Among authors: simas abc. Biomolecules. 2019 Oct 8;9(10):583. doi: 10.3390/biom9100583. Biomolecules. 2019. PMID: 31597234 Free PMC article.
11 results