Whysner J - Search Results

1

Mutagenicity of benzo[b]phenanthro[2,3-d]thiophene (BPT) and its metabolites in TA100 and base-specific tester strains (TA7001-TA7006) of Salmonella typhimurium: evidence of multiple pathways for the bioactivation of BPT.

Kumar S, Lin JM, Whysner J, Sikka HC, Amin S. Kumar S, et al. Among authors: whysner j. Mutat Res. 2004 Jan 12;545(1-2):11-21. doi: 10.1016/s0027-5107(03)00138-6. Mutat Res. 2004. PMID: 14698413

2

Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.

Yang YM, Conaway CC, Chiao JW, Wang CX, Amin S, Whysner J, Dai W, Reinhardt J, Chung FL. Yang YM, et al. Among authors: whysner j. Cancer Res. 2002 Jan 1;62(1):2-7. Cancer Res. 2002. PMID: 11782348

3

Genotoxicity of benzene and its metabolites.

Whysner J, Reddy MV, Ross PM, Mohan M, Lax EA. Whysner J, et al. Mutat Res. 2004 Mar;566(2):99-130. doi: 10.1016/s1383-5742(03)00053-x. Mutat Res. 2004. PMID: 15164977 Review.

4

Evaluation of possible genotoxic mechanisms for acrylonitrile tumorigenicity.

Whysner J, Ross PM, Conaway CC, Verna LK, Williams GM. Whysner J, et al. Regul Toxicol Pharmacol. 1998 Jun;27(3):217-39. doi: 10.1006/rtph.1998.1204. Regul Toxicol Pharmacol. 1998. PMID: 9693074 Review.

5

Mechanistic considerations in risk assessment for epigenetic tumor-promoting carcinogens.

Williams GM, Whysner J. Williams GM, et al. Among authors: whysner j. Prog Clin Biol Res. 1995;391:369-83. Prog Clin Biol Res. 1995. PMID: 8532729 Review. No abstract available.

6

Hepatocellular iron accumulation and increased cell proliferation in polychlorinated biphenyl-exposed Sprague-Dawley rats and the development of hepatocarcinogenesis.

Whysner J, Wang CX. Whysner J, et al. Toxicol Sci. 2001 Jul;62(1):36-45. doi: 10.1093/toxsci/62.1.36. Toxicol Sci. 2001. PMID: 11399791

7

Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1.

Gulati AP, Yang YM, Harter D, Mukhopadhyay A, Aggarwal BB, Benzil DL, Whysner J, Albino AP, Murali R, Jhanwar-Uniyal M. Gulati AP, et al. Among authors: whysner j. Mol Carcinog. 2006 Jan;45(1):26-37. doi: 10.1002/mc.20149. Mol Carcinog. 2006. PMID: 16267831

8

Vinyl chloride mechanistic data and risk assessment: DNA reactivity and cross-species quantitative risk extrapolation.

Whysner J, Conaway CC, Verna L, Williams GM. Whysner J, et al. Pharmacol Ther. 1996;71(1-2):7-28. doi: 10.1016/0163-7258(96)00060-5. Pharmacol Ther. 1996. PMID: 8910947 Review.

9

Formaldehyde mechanistic data and risk assessment: endogenous protection from DNA adduct formation.

Conaway CC, Whysner J, Verna LK, Williams GM. Conaway CC, et al. Among authors: whysner j. Pharmacol Ther. 1996;71(1-2):29-55. doi: 10.1016/0163-7258(96)00061-7. Pharmacol Ther. 1996. PMID: 8910948 Review.

10

Formation of 8-oxodeoxyguanosine in brain DNA of rats exposed to acrylonitrile.

Whysner J, Steward RE 3rd, Chen D, Conaway CC, Verna LK, Richie JP Jr, Ali N, Williams GM. Whysner J, et al. Arch Toxicol. 1998 Jun;72(7):429-38. doi: 10.1007/s002040050523. Arch Toxicol. 1998. PMID: 9708882

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