Khoo J - Search Results

1

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.

Alp NJ, McAteer MA, Khoo J, Choudhury RP, Channon KM. Alp NJ, et al. Among authors: khoo j. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):445-50. doi: 10.1161/01.ATV.0000115637.48689.77. Epub 2004 Jan 5. Arterioscler Thromb Vasc Biol. 2004. PMID: 14707037

2

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.

Alp NJ, Mussa S, Khoo J, Cai S, Guzik T, Jefferson A, Goh N, Rockett KA, Channon KM. Alp NJ, et al. Among authors: khoo j. J Clin Invest. 2003 Sep;112(5):725-35. doi: 10.1172/JCI17786. J Clin Invest. 2003. PMID: 12952921 Free PMC article.

3

EPR quantification of vascular nitric oxide production in genetically modified mouse models.

Khoo JP, Alp NJ, Bendall JK, Kawashima S, Yokoyama M, Zhang YH, Casadei B, Channon KM. Khoo JP, et al. Nitric Oxide. 2004 May;10(3):156-61. doi: 10.1016/j.niox.2004.04.003. Nitric Oxide. 2004. PMID: 15158695

4

Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse.

Khoo JP, Nicoli T, Alp NJ, Fullerton J, Flint J, Channon KM. Khoo JP, et al. Mol Genet Metab. 2004 Jul;82(3):251-4. doi: 10.1016/j.ymgme.2004.04.006. Mol Genet Metab. 2004. PMID: 15234340

5

Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.

Cai S, Khoo J, Channon KM. Cai S, et al. Among authors: khoo j. Cardiovasc Res. 2005 Mar 1;65(4):823-31. doi: 10.1016/j.cardiores.2004.10.040. Cardiovasc Res. 2005. PMID: 15721862

6

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.

Khoo JP, Zhao L, Alp NJ, Bendall JK, Nicoli T, Rockett K, Wilkins MR, Channon KM. Khoo JP, et al. Circulation. 2005 Apr 26;111(16):2126-33. doi: 10.1161/01.CIR.0000162470.26840.89. Epub 2005 Apr 11. Circulation. 2005. PMID: 15824200

7

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.

Cai S, Khoo J, Mussa S, Alp NJ, Channon KM. Cai S, et al. Among authors: khoo j. Diabetologia. 2005 Sep;48(9):1933-40. doi: 10.1007/s00125-005-1857-5. Epub 2005 Jul 21. Diabetologia. 2005. PMID: 16034613

8

Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.

Adlam D, Bendall JK, De Bono JP, Alp NJ, Khoo J, Nicoli T, Yokoyama M, Kawashima S, Channon KM. Adlam D, et al. Among authors: khoo j. Exp Physiol. 2007 Jan;92(1):119-26. doi: 10.1113/expphysiol.2006.035113. Epub 2006 Sep 28. Exp Physiol. 2007. PMID: 17012144 Free article.

9

Tetrahydrobiopterin supplementation reduces atherosclerosis and vascular inflammation in apolipoprotein E-knockout mice.

Schmidt TS, McNeill E, Douglas G, Crabtree MJ, Hale AB, Khoo J, O'Neill CA, Cheng A, Channon KM, Alp NJ. Schmidt TS, et al. Among authors: khoo j. Clin Sci (Lond). 2010 May 6;119(3):131-42. doi: 10.1042/CS20090559. Clin Sci (Lond). 2010. PMID: 20337596

10

Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) Study.

Singh A, Greenwood JP, Berry C, Dawson DK, Hogrefe K, Kelly DJ, Dhakshinamurthy V, Lang CC, Khoo JP, Sprigings D, Steeds RP, Jerosch-Herold M, Neubauer S, Prendergast B, Williams B, Zhang R, Hudson I, Squire IB, Ford I, Samani NJ, McCann GP. Singh A, et al. Among authors: khoo jp. Eur Heart J. 2017 Apr 21;38(16):1222-1229. doi: 10.1093/eurheartj/ehx001. Eur Heart J. 2017. PMID: 28204448 Free PMC article.

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