Osawa Y - Search Results

1

Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice.

Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H. Imose M, et al. Among authors: osawa y. Liver Int. 2003 Oct;23(5):386-96. doi: 10.1034/j.1478-3231.2003.00867.x. Liver Int. 2003. PMID: 14708901

2

Tumor necrosis factor alpha-induced interleukin-8 production via NF-kappaB and phosphatidylinositol 3-kinase/Akt pathways inhibits cell apoptosis in human hepatocytes.

Osawa Y, Nagaki M, Banno Y, Brenner DA, Asano T, Nozawa Y, Moriwaki H, Nakashima S. Osawa Y, et al. Infect Immun. 2002 Nov;70(11):6294-301. doi: 10.1128/IAI.70.11.6294-6301.2002. Infect Immun. 2002. PMID: 12379708 Free PMC article.

3

Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation.

Osawa Y, Nagaki M, Banno Y, Brenner DA, Nozawa Y, Moriwaki H, Nakashima S. Osawa Y, et al. J Immunol. 2003 Apr 15;170(8):4053-60. doi: 10.4049/jimmunol.170.8.4053. J Immunol. 2003. PMID: 12682234

4

Leflunomide protects from T-cell-mediated liver injury in mice through inhibition of nuclear factor kappaB.

Imose M, Nagaki M, Kimura K, Takai S, Imao M, Naiki T, Osawa Y, Asano T, Hayashi H, Moriwaki H. Imose M, et al. Among authors: osawa y. Hepatology. 2004 Nov;40(5):1160-9. doi: 10.1002/hep.20438. Hepatology. 2004. PMID: 15455409

5

Normal liver regeneration and liver cell apoptosis after partial hepatectomy in tumor necrosis factor-alpha-deficient mice.

Hayashi H, Nagaki M, Imose M, Osawa Y, Kimura K, Takai S, Imao M, Naiki T, Kato T, Moriwaki H. Hayashi H, et al. Among authors: osawa y. Liver Int. 2005 Feb;25(1):162-70. doi: 10.1111/j.1478-3231.2005.01029.x. Liver Int. 2005. PMID: 15698414

6

Extracellular matrix is required for the survival and differentiation of transplanted hepatic progenitor cells.

Tsukada Y, Nagaki M, Suetsugu A, Osawa Y, Moriwaki H. Tsukada Y, et al. Among authors: osawa y. Biochem Biophys Res Commun. 2009 Apr 17;381(4):733-7. doi: 10.1016/j.bbrc.2009.02.158. Epub 2009 Mar 4. Biochem Biophys Res Commun. 2009. PMID: 19268430

7

Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice.

Osawa Y, Seki E, Adachi M, Suetsugu A, Ito H, Moriwaki H, Seishima M, Nagaki M. Osawa Y, et al. Hepatology. 2010 Jan;51(1):237-45. doi: 10.1002/hep.23262. Hepatology. 2010. PMID: 19821528

8

Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression.

Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M. Osawa Y, et al. FASEB J. 2011 Apr;25(4):1133-44. doi: 10.1096/fj.10-168351. Epub 2010 Dec 16. FASEB J. 2011. PMID: 21163859 Free PMC article.

9

Liver injury induced by lipopolysaccharide is mediated by TNFR-1 but not by TNFR-2 or Fas in mice.

Shimizu S, Yamada Y, Okuno M, Ohnishi H, Osawa Y, Seishima M, Moriwaki H. Shimizu S, et al. Among authors: osawa y. Hepatol Res. 2005 Mar;31(3):136-42. doi: 10.1016/j.hepres.2004.11.012. Epub 2005 Feb 8. Hepatol Res. 2005. PMID: 15715973

10

Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha.

Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA. Osawa Y, et al. J Biol Chem. 2005 Jul 29;280(30):27879-87. doi: 10.1074/jbc.M503002200. Epub 2005 Jun 9. J Biol Chem. 2005. PMID: 15946935 Free article.

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