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TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. Latz E, et al. Among authors: visintin a. Nat Immunol. 2004 Feb;5(2):190-8. doi: 10.1038/ni1028. Epub 2004 Jan 11. Nat Immunol. 2004. PMID: 14716310
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Latz E, Visintin A, Lien E, Fitzgerald KA, Monks BG, Kurt-Jones EA, Golenbock DT, Espevik T. Latz E, et al. Among authors: visintin a. J Biol Chem. 2002 Dec 6;277(49):47834-43. doi: 10.1074/jbc.M207873200. Epub 2002 Sep 24. J Biol Chem. 2002. PMID: 12324469 Free article.
Mechanisms of TLR9 activation.
Latz E, Visintin A, Espevik T, Golenbock DT. Latz E, et al. Among authors: visintin a. J Endotoxin Res. 2004;10(6):406-12. doi: 10.1179/096805104225006525. J Endotoxin Res. 2004. PMID: 15588423
MD-2.
Visintin A, Iliev DB, Monks BG, Halmen KA, Golenbock DT. Visintin A, et al. Immunobiology. 2006;211(6-8):437-47. doi: 10.1016/j.imbio.2006.05.010. Epub 2006 Jul 18. Immunobiology. 2006. PMID: 16920483 Review.
76 results