Frade R - Search Results

1

Inhibition of tumorigenicity and metastasis of human melanoma cells by anti-cathepsin L single chain variable fragment.

Rousselet N, Mills L, Jean D, Tellez C, Bar-Eli M, Frade R. Rousselet N, et al. Among authors: frade r. Cancer Res. 2004 Jan 1;64(1):146-51. doi: 10.1158/0008-5472.can-03-1717. Cancer Res. 2004. PMID: 14729618

2

Characterization of human cathepsin L promoter and identification of binding sites for NF-Y, Sp1 and Sp3 that are essential for its activity.

Jean D, Guillaume N, Frade R. Jean D, et al. Among authors: frade r. Biochem J. 2002 Jan 1;361(Pt 1):173-84. doi: 10.1042/0264-6021:3610173. Biochem J. 2002. PMID: 11742542 Free PMC article.

3

Cloning and characterization of anti-cathepsin L single chain variable fragment whose expression inhibits procathepsin L secretion in human melanoma cells.

Guillaume-Rousselet N, Jean D, Frade R. Guillaume-Rousselet N, et al. Among authors: frade r. Biochem J. 2002 Oct 1;367(Pt 1):219-27. doi: 10.1042/BJ20020350. Biochem J. 2002. PMID: 12241546 Free PMC article.

4

Cathepsin L expression is up-regulated by hypoxia in human melanoma cells: role of its 5'-untranslated region.

Jean D, Rousselet N, Frade R. Jean D, et al. Among authors: frade r. Biochem J. 2008 Jul 1;413(1):125-34. doi: 10.1042/BJ20071255. Biochem J. 2008. PMID: 18366346

5

Down-regulation of the expression of RB18A/MED1, a cofactor of transcription, triggers strong tumorigenic phenotype of human melanoma cells.

Ndong Jde L, Jean D, Rousselet N, Frade R. Ndong Jde L, et al. Among authors: frade r. Int J Cancer. 2009 Jun 1;124(11):2597-606. doi: 10.1002/ijc.24253. Int J Cancer. 2009. PMID: 19243021

6

A cysteine proteinase, which cleaves human C3, the third component of complement, is involved in tumorigenicity and metastasis of human melanoma.

Jean D, Bar-Eli M, Huang S, Xie K, Rodrigues-Lima F, Hermann J, Frade R. Jean D, et al. Among authors: frade r. Cancer Res. 1996 Jan 15;56(2):254-8. Cancer Res. 1996. PMID: 8542576

7

Procathepsin-L, a proteinase that cleaves human C3 (the third component of complement), confers high tumorigenic and metastatic properties to human melanoma cells.

Frade R, Rodrigues-Lima F, Huang S, Xie K, Guillaume N, Bar-Eli M. Frade R, et al. Cancer Res. 1998 Jul 1;58(13):2733-6. Cancer Res. 1998. PMID: 9661883

8

Expression of cathepsin L in human tumor cells is under the control of distinct regulatory mechanisms.

Jean D, Rousselet N, Frade R. Jean D, et al. Among authors: frade r. Oncogene. 2006 Mar 9;25(10):1474-84. doi: 10.1038/sj.onc.1209196. Oncogene. 2006. PMID: 16261157

9

Intratumoral gene delivery of anti-cathepsin L single-chain variable fragment by lentiviral vector inhibits tumor progression induced by human melanoma cells.

Frade R, Rousselet N, Jean D. Frade R, et al. Cancer Gene Ther. 2008 Sep;15(9):591-604. doi: 10.1038/cgt.2008.51. Epub 2008 Jul 11. Cancer Gene Ther. 2008. PMID: 18617916

10

Identification on melanoma cells of p39, a cysteine proteinase that cleaves C3, the third component of complement: amino-acid-sequence identities with procathepsin L.

Jean D, Hermann J, Rodrigues-Lima F, Barel M, Balbo M, Frade R. Jean D, et al. Among authors: frade r. Biochem J. 1995 Dec 15;312 ( Pt 3)(Pt 3):961-9. doi: 10.1042/bj3120961. Biochem J. 1995. PMID: 8554545 Free PMC article.

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