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WRN inhibition leads to its chromatin-associated degradation via the PIAS4-RNF4-p97/VCP axis.
Rodríguez Pérez F, Natwick D, Schiff L, McSwiggen D, Heckert A, Huey M, Morrison H, Loo M, Miranda RG, Filbin J, Ortega J, Van Buren K, Murnock D, Tao A, Butler R, Cheng K, Tarvestad W, Zhang Z, Gonzalez E, Miller RM, Kelly M, Tang Y, Ho J, Anderson D, Bashore C, Basham S. Rodríguez Pérez F, et al. Among authors: huey m. Nat Commun. 2024 Jul 18;15(1):6059. doi: 10.1038/s41467-024-50178-3. Nat Commun. 2024. PMID: 39025847 Free PMC article.
31 results