Mitani H - Search Results

1

A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer.

Okimoto K, Sakurai J, Kobayashi T, Mitani H, Hirayama Y, Nickerson ML, Warren MB, Zbar B, Schmidt LS, Hino O. Okimoto K, et al. Among authors: mitani h. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2023-7. doi: 10.1073/pnas.0308071100. Epub 2004 Feb 9. Proc Natl Acad Sci U S A. 2004. PMID: 14769940 Free PMC article.

2

Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-type Tsc2 gene.

Kobayashi T, Mitani H, Takahashi R, Hirabayashi M, Ueda M, Tamura H, Hino O. Kobayashi T, et al. Among authors: mitani h. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3990-3. doi: 10.1073/pnas.94.8.3990. Proc Natl Acad Sci U S A. 1997. PMID: 9108092 Free PMC article.

3

A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.

Kobayashi T, Minowa O, Sugitani Y, Takai S, Mitani H, Kobayashi E, Noda T, Hino O. Kobayashi T, et al. Among authors: mitani h. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8762-7. doi: 10.1073/pnas.151033798. Epub 2001 Jul 3. Proc Natl Acad Sci U S A. 2001. PMID: 11438694 Free PMC article.

4

N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat.

Satake N, Miyagawa M, Sakurai J, Mitani H, Kobayashi T, Tamura H, Hino O. Satake N, et al. Among authors: mitani h. Cancer Lett. 2002 Oct 28;184(2):157-63. doi: 10.1016/s0304-3835(02)00209-4. Cancer Lett. 2002. PMID: 12127687

5

Identification of the coding sequences responsible for Tsc2-mediated tumor suppression using a transgenic rat system.

Momose S, Kobayashi T, Mitani H, Hirabayashi M, Ito K, Ueda M, Nabeshima Y, Hino O. Momose S, et al. Among authors: mitani h. Hum Mol Genet. 2002 Nov 15;11(24):2997-3006. doi: 10.1093/hmg/11.24.2997. Hum Mol Genet. 2002. PMID: 12417521

6

Presence of a modifier gene(s) affecting early renal carcinogenesis in the Tsc2 mutant (Eker) rat model.

Kikuchi Y, Sudo A, Mitani H, Hino O. Kikuchi Y, et al. Among authors: mitani h. Int J Oncol. 2004 Jan;24(1):75-80. Int J Oncol. 2004. PMID: 14654943

7

Niban gene is commonly expressed in the renal tumors: a new candidate marker for renal carcinogenesis.

Adachi H, Majima S, Kon S, Kobayashi T, Kajino K, Mitani H, Hirayama Y, Shiina H, Igawa M, Hino O. Adachi H, et al. Among authors: mitani h. Oncogene. 2004 Apr 22;23(19):3495-500. doi: 10.1038/sj.onc.1207468. Oncogene. 2004. PMID: 14990989

8

Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2).

Hino O, Kobayashi E, Hirayama Y, Kobayashi T, Kubo Y, Tsuchiya H, Kikuchi Y, Mitani H. Hino O, et al. Among authors: mitani h. Mol Carcinog. 1995 Sep;14(1):23-7. doi: 10.1002/mc.2940140106. Mol Carcinog. 1995. PMID: 7546221

9

Allelic loss at the tuberous sclerosis (Tsc2) gene locus in spontaneous uterine leiomyosarcomas and pituitary adenomas in the Eker rat model.

Kubo Y, Kikuchi Y, Mitani H, Kobayashi E, Kobayashi T, Hino O. Kubo Y, et al. Among authors: mitani h. Jpn J Cancer Res. 1995 Sep;86(9):828-32. doi: 10.1111/j.1349-7006.1995.tb03092.x. Jpn J Cancer Res. 1995. PMID: 7591959 Free PMC article.

10

The EKER rat, a model of dominantly inherited cancer syndrome.

Hino O, Kobayashi T, Mitani H, Kobayashi E, Kubo Y, Tsuchiya H, Kikuchi Y, Nishizawa M, Hirayama Y. Hino O, et al. Among authors: mitani h. Transplant Proc. 1995 Apr;27(2):1529-31. Transplant Proc. 1995. PMID: 7725400 No abstract available.

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