Finn J - Search Results

1

A series of heterocyclic inhibitors of phenylalanyl-tRNA synthetases with antibacterial activity.

Yu XY, Finn J, Hill JM, Wang ZG, Keith D, Silverman J, Oliver N. Yu XY, et al. Among authors: finn j. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1343-6. doi: 10.1016/j.bmcl.2003.11.082. Bioorg Med Chem Lett. 2004. PMID: 14980695

2

Discovery of a potent and selective series of pyrazole bacterial methionyl-tRNA synthetase inhibitors.

Finn J, Mattia K, Morytko M, Ram S, Yang Y, Wu X, Mak E, Gallant P, Keith D. Finn J, et al. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2231-4. doi: 10.1016/s0960-894x(03)00298-1. Bioorg Med Chem Lett. 2003. PMID: 12798340

3

Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin.

Hill J, Siedlecki J, Parr I, Morytko M, Yu X, Zhang Y, Silverman J, Controneo N, Laganas V, Li T, Lai JJ, Keith D, Shimer G, Finn J. Hill J, et al. Among authors: finn j. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4187-91. doi: 10.1016/j.bmcl.2003.07.019. Bioorg Med Chem Lett. 2003. PMID: 14622998

4

Array synthesis of novel lipodepsipeptide.

Siedlecki J, Hill J, Parr I, Yu X, Morytko M, Zhang Y, Silverman J, Controneo N, Laganas V, Li T, Li J, Keith D, Shimer G, Finn J. Siedlecki J, et al. Among authors: finn j. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4245-9. doi: 10.1016/j.bmcl.2003.07.025. Bioorg Med Chem Lett. 2003. PMID: 14623010

5

A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl-tRNA synthetases.

Yu XY, Finn J, Hill JM, Wang ZG, Keith D, Silverman J, Oliver N. Yu XY, et al. Among authors: finn j. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1339-42. doi: 10.1016/j.bmcl.2003.11.081. Bioorg Med Chem Lett. 2004. PMID: 14980694

6

A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase.

Yu XY, Hill JM, Yu G, Yang Y, Kluge AF, Keith D, Finn J, Gallant P, Silverman J, Lim A. Yu XY, et al. Among authors: finn j. Bioorg Med Chem Lett. 2001 Feb 26;11(4):541-4. doi: 10.1016/s0960-894x(00)00697-1. Bioorg Med Chem Lett. 2001. PMID: 11229766

7

Regulation of mprF by antisense RNA restores daptomycin susceptibility to daptomycin-resistant isolates of Staphylococcus aureus.

Rubio A, Conrad M, Haselbeck RJ, G C K, Brown-Driver V, Finn J, Silverman JA. Rubio A, et al. Among authors: finn j. Antimicrob Agents Chemother. 2011 Jan;55(1):364-7. doi: 10.1128/AAC.00429-10. Epub 2010 Oct 25. Antimicrob Agents Chemother. 2011. PMID: 20974866 Free PMC article.

8

Identification of novel inhibitors of methionyl-tRNA synthetase (MetRS) by virtual screening.

Finn J, Stidham M, Hilgers M, G C K. Finn J, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3932-7. doi: 10.1016/j.bmcl.2008.06.032. Epub 2008 Jun 13. Bioorg Med Chem Lett. 2008. PMID: 18590962

9

High-throughput synthesis optimization of sulfonamide NPY Y5 antagonists.

Finn J, Pelham D, Walker MW, Gluchowski C. Finn J, et al. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1771-4. doi: 10.1016/s0960-894x(02)00288-3. Bioorg Med Chem Lett. 2002. PMID: 12067558

10

Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.

Li X, Hilgers M, Cunningham M, Chen Z, Trzoss M, Zhang J, Kohnen L, Lam T, Creighton C, G C K, Nelson K, Kwan B, Stidham M, Brown-Driver V, Shaw KJ, Finn J. Li X, et al. Among authors: finn j. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5171-6. doi: 10.1016/j.bmcl.2011.07.059. Epub 2011 Jul 23. Bioorg Med Chem Lett. 2011. PMID: 21831637

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