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Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Heymans S, Luttun A, Nuyens D, Theilmeier G, Creemers E, Moons L, Dyspersin GD, Cleutjens JP, Shipley M, Angellilo A, Levi M, Nübe O, Baker A, Keshet E, Lupu F, Herbert JM, Smits JF, Shapiro SD, Baes M, Borgers M, Collen D, Daemen MJ, Carmeliet P. Heymans S, et al. Among authors: carmeliet p. Nat Med. 1999 Oct;5(10):1135-42. doi: 10.1038/13459. Nat Med. 1999. PMID: 10502816
Angiogenesis in cancer and other diseases.
Carmeliet P, Jain RK. Carmeliet P, et al. Nature. 2000 Sep 14;407(6801):249-57. doi: 10.1038/35025220. Nature. 2000. PMID: 11001068 Review.
Molecular mechanisms of blood vessel growth.
Conway EM, Collen D, Carmeliet P. Conway EM, et al. Among authors: carmeliet p. Cardiovasc Res. 2001 Feb 16;49(3):507-21. doi: 10.1016/s0008-6363(00)00281-9. Cardiovasc Res. 2001. PMID: 11166264 Review.
784 results