Waddell ID - Search Results

1

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators.

Brocklehurst KJ, Payne VA, Davies RA, Carroll D, Vertigan HL, Wightman HJ, Aiston S, Waddell ID, Leighton B, Coghlan MP, Agius L. Brocklehurst KJ, et al. Among authors: waddell id. Diabetes. 2004 Mar;53(3):535-41. doi: 10.2337/diabetes.53.3.535. Diabetes. 2004. PMID: 14988235

2

Clenbuterol is not an agonist of Na+ dependent creatine transport.

Thorpe KA, Brocklehurst KJ, Blackburn SJ, Holloway BR, Waddell ID. Thorpe KA, et al. Among authors: waddell id. Biochem Soc Trans. 1996 May;24(2):215S. doi: 10.1042/bst024215s. Biochem Soc Trans. 1996. PMID: 8736873 No abstract available.

3

Anabolic effects of a range of beta 2-adrenoceptor agonists in a clonal G8.P8 cell line.

Blackburn SJ, Brocklehurst KJ, Thorpe KA, Holloway BR, Waddell ID. Blackburn SJ, et al. Among authors: waddell id. Biochem Soc Trans. 1996 May;24(2):214S. doi: 10.1042/bst024214s. Biochem Soc Trans. 1996. PMID: 8736872 No abstract available.

4

Increased expression of several components of the ATP dependant proteosome pathway in denervated rat muscle is reversed by beta 2-adrenergic agonists.

Waddell ID, Ruddock P, Brocklehurst KJ, Wilbraham JM, Worral V, Holloway BR. Waddell ID, et al. Biochem Soc Trans. 1998 Nov;26(4):S311. doi: 10.1042/bst026s311. Biochem Soc Trans. 1998. PMID: 10047825 No abstract available.

5

Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides.

Waszkowycz B, Smith KM, McGonagle AE, Jordan AM, Acton B, Fairweather EE, Griffiths LA, Hamilton NM, Hamilton NS, Hitchin JR, Hutton CP, James DI, Jones CD, Jones S, Mould DP, Small HF, Stowell AIJ, Tucker JA, Waddell ID, Ogilvie DJ. Waszkowycz B, et al. Among authors: waddell id. J Med Chem. 2018 Dec 13;61(23):10767-10792. doi: 10.1021/acs.jmedchem.8b01407. Epub 2018 Nov 19. J Med Chem. 2018. PMID: 30403352

6

First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib.

James DI, Smith KM, Jordan AM, Fairweather EE, Griffiths LA, Hamilton NS, Hitchin JR, Hutton CP, Jones S, Kelly P, McGonagle AE, Small H, Stowell AI, Tucker J, Waddell ID, Waszkowycz B, Ogilvie DJ. James DI, et al. Among authors: waddell id. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190. doi: 10.1021/acschembio.6b00609. Epub 2016 Oct 12. ACS Chem Biol. 2016. PMID: 27689388

7

Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha.

Li YP, Schwartz RJ, Waddell ID, Holloway BR, Reid MB. Li YP, et al. Among authors: waddell id. FASEB J. 1998 Jul;12(10):871-80. doi: 10.1096/fasebj.12.10.971. FASEB J. 1998. PMID: 9657527

8

Leptin and its relation to weight loss, ob gene expression and the acute-phase response in surgical patients.

Moses AG, Dowidar N, Holloway B, Waddell I, Fearon KC, Ross JA. Moses AG, et al. Br J Surg. 2001 Apr;88(4):588-93. doi: 10.1046/j.1365-2168.2001.01743.x. Br J Surg. 2001. PMID: 11298630

9

Activation of hepatic microsomal glucose-6-phosphate transport by prostaglandins.

Orme RM, Waddell ID, Hume R, Burchell A. Orme RM, et al. Among authors: waddell id. Biochem Soc Trans. 1990 Dec;18(6):1252-3. doi: 10.1042/bst0181252. Biochem Soc Trans. 1990. PMID: 2088897 No abstract available.

10

A high-throughput screening-compatible homogeneous time-resolved fluorescence assay measuring the glycohydrolase activity of human poly(ADP-ribose) glycohydrolase.

Stowell AI, James DI, Waddell ID, Bennett N, Truman C, Hardern IM, Ogilvie DJ. Stowell AI, et al. Among authors: waddell id. Anal Biochem. 2016 Jun 15;503:58-64. doi: 10.1016/j.ab.2016.03.016. Epub 2016 Mar 29. Anal Biochem. 2016. PMID: 27036617

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