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Page 1
Molecular determinants of vanilloid sensitivity in TRPV1.
Gavva NR, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, Zhang TJ, Viswanadhan VN, Toth A, Pearce LV, Vanderah TW, Porreca F, Blumberg PM, Lile J, Sun Y, Wild K, Louis JC, Treanor JJ. Gavva NR, et al. Among authors: pearce lv. J Biol Chem. 2004 May 7;279(19):20283-95. doi: 10.1074/jbc.M312577200. Epub 2004 Mar 2. J Biol Chem. 2004. PMID: 14996838 Free article.
N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.
Lee J, Lee J, Kang M, Shin M, Kim JM, Kang SU, Lim JO, Choi HK, Suh YG, Park HG, Oh U, Kim HD, Park YH, Ha HJ, Kim YH, Toth A, Wang Y, Tran R, Pearce LV, Lundberg DJ, Blumberg PM. Lee J, et al. Among authors: pearce lv. J Med Chem. 2003 Jul 3;46(14):3116-26. doi: 10.1021/jm030089u. J Med Chem. 2003. PMID: 12825950
Kinetics of penetration influence the apparent potency of vanilloids on TRPV1.
Lazar J, Braun DC, Tóth A, Wang Y, Pearce LV, Pavlyukovets VA, Blumberg PM, Garfield SH, Wincovitch S, Choi HK, Lee J. Lazar J, et al. Among authors: pearce lv. Mol Pharmacol. 2006 Apr;69(4):1166-73. doi: 10.1124/mol.105.019158. Epub 2006 Jan 17. Mol Pharmacol. 2006. PMID: 16418338
Alpha-substituted N-(4-tert-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists.
Chung JU, Kim SY, Lim JO, Choi HK, Kang SU, Yoon HS, Ryu H, Kang DW, Lee J, Kang B, Choi S, Toth A, Pearce LV, Pavlyukovets VA, Lundberg DJ, Blumberg PM. Chung JU, et al. Among authors: pearce lv. Bioorg Med Chem. 2007 Sep 15;15(18):6043-53. doi: 10.1016/j.bmc.2007.06.041. Epub 2007 Jun 26. Bioorg Med Chem. 2007. PMID: 17629487
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Choi HK, Choi S, Lee Y, Kang DW, Ryu H, Maeng HJ, Chung SJ, Pavlyukovets VA, Pearce LV, Toth A, Tran R, Wang Y, Morgan MA, Blumberg PM, Lee J. Choi HK, et al. Among authors: pearce lv. Bioorg Med Chem. 2009 Jan 15;17(2):690-8. doi: 10.1016/j.bmc.2008.11.085. Epub 2008 Dec 25. Bioorg Med Chem. 2009. PMID: 19135377 Free PMC article.
53 results