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Page 1
A non-peptide NK1 receptor agonist showing subpicomolar affinity.
Cappelli A, Giuliani G, Pericot Mohr Gl Gl, Gallelli A, Anzini M, Vomero S, Cupello A, Scarrone S, Matarrese M, Moresco RM, Fazio F, Finetti F, Morbidelli L, Ziche M. Cappelli A, et al. Among authors: vomero s. J Med Chem. 2004 Mar 11;47(6):1315-8. doi: 10.1021/jm034219a. J Med Chem. 2004. PMID: 14998319
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity.
Anzini M, Canullo L, Braile C, Cappelli A, Gallelli A, Vomero S, Menziani MC, De Benedetti PG, Rizzo M, Collina S, Azzolina O, Sbacchi M, Ghelardini C, Galeotti N. Anzini M, et al. Among authors: vomero s. J Med Chem. 2003 Aug 28;46(18):3853-64. doi: 10.1021/jm0307640. J Med Chem. 2003. PMID: 12930147
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.
Cappelli A, Pericot Mohr Gl Gl, Gallelli A, Rizzo M, Anzini M, Vomero S, Mennuni L, Ferrari F, Makovec F, Menziani MC, De Benedetti PG, Giorgi G. Cappelli A, et al. Among authors: vomero s. J Med Chem. 2004 May 6;47(10):2574-86. doi: 10.1021/jm031100t. J Med Chem. 2004. PMID: 15115399
Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties.
Cappelli A, Gallelli A, Manini M, Anzini M, Mennuni L, Makovec F, Menziani MC, Alcaro S, Ortuso F, Vomero S. Cappelli A, et al. Among authors: vomero s. J Med Chem. 2005 May 19;48(10):3564-75. doi: 10.1021/jm0493461. J Med Chem. 2005. PMID: 15887964
Synthesis, labeling, and biological evaluation of halogenated 2-quinolinecarboxamides as potential radioligands for the visualization of peripheral benzodiazepine receptors.
Cappelli A, Matarrese M, Moresco RM, Valenti S, Anzini M, Vomero S, Turolla EA, Belloli S, Simonelli P, Filannino MA, Lecchi M, Fazio F. Cappelli A, et al. Among authors: vomero s. Bioorg Med Chem. 2006 Jun 15;14(12):4055-66. doi: 10.1016/j.bmc.2006.02.004. Epub 2006 Feb 21. Bioorg Med Chem. 2006. PMID: 16495062
Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds.
Cappelli A, Pericot Mohr Gl, Giuliani G, Galeazzi S, Anzini M, Mennuni L, Ferrari F, Makovec F, Kleinrath EM, Langer T, Valoti M, Giorgi G, Vomero S. Cappelli A, et al. Among authors: vomero s. J Med Chem. 2006 Nov 2;49(22):6451-64. doi: 10.1021/jm0603163. J Med Chem. 2006. PMID: 17064065
70 results