Sorger D - Search Results

1

Synthesis of novel 4- and 5-substituted benzyl ether derivatives of vesamicol and in vitro evaluation of their binding properties to the vesicular acetylcholine transporter site.

Scheunemann M, Sorger D, Wenzel B, Heinitz K, Schliebs R, Klingner M, Sabri O, Steinbach J. Scheunemann M, et al. Among authors: sorger d. Bioorg Med Chem. 2004 Mar 15;12(6):1459-65. doi: 10.1016/j.bmc.2003.12.035. Bioorg Med Chem. 2004. PMID: 15018919

2

Structural changes of benzylether derivatives of vesamicol and their influence on the binding selectivity to the vesicular acetylcholine transporter.

Wenzel B, Sorger D, Heinitz K, Scheunemann M, Schliebs R, Steinbach J, Sabri O. Wenzel B, et al. Among authors: sorger d. Eur J Med Chem. 2005 Dec;40(12):1197-205. doi: 10.1016/j.ejmech.2005.06.007. Epub 2005 Aug 10. Eur J Med Chem. 2005. PMID: 16095762

3

A new 18F-labeled fluoroacetylmorpholino derivative of vesamicol for neuroimaging of the vesicular acetylcholine transporter.

Sorger D, Scheunemann M, Grossmann U, Fischer S, Vercouille J, Hiller A, Wenzel B, Roghani A, Schliebs R, Brust P, Sabri O, Steinbach J. Sorger D, et al. Nucl Med Biol. 2008 Feb;35(2):185-95. doi: 10.1016/j.nucmedbio.2007.10.004. Nucl Med Biol. 2008. PMID: 18312828

4

Pyrrolovesamicols--synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers.

Wenzel B, Li Y, Kraus W, Sorger D, Sabri O, Brust P, Steinbach J. Wenzel B, et al. Among authors: sorger d. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2163-6. doi: 10.1016/j.bmcl.2012.01.127. Epub 2012 Feb 4. Bioorg Med Chem Lett. 2012. PMID: 22365760

5

New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure.

Barthel C, Sorger D, Deuther-Conrad W, Scheunemann M, Schweiger S, Jäckel P, Roghani A, Steinbach J, Schüürmann G, Sabri O, Brust P, Wenzel B. Barthel C, et al. Among authors: sorger d. Eur J Med Chem. 2015 Jul 15;100:50-67. doi: 10.1016/j.ejmech.2015.05.033. Epub 2015 May 22. Eur J Med Chem. 2015. PMID: 26071858

6

Neuroimaging of the vesicular acetylcholine transporter by a novel 4-[18F]fluoro-benzoyl derivative of 7-hydroxy-6-(4-phenyl-piperidin-1-yl)-octahydro-benzo[1,4]oxazines.

Sorger D, Scheunemann M, Vercouillie J, Grossmann U, Fischer S, Hiller A, Wenzel B, Roghani A, Schliebs R, Steinbach J, Brust P, Sabri O. Sorger D, et al. Nucl Med Biol. 2009 Jan;36(1):17-27. doi: 10.1016/j.nucmedbio.2008.10.006. Nucl Med Biol. 2009. PMID: 19181265

7

Adduct of 2-[18F]FDG and 2-nitroimidazole as a putative radiotracer for the detection of hypoxia with PET: synthesis, in vitro- and in vivo-characterization.

Patt M, Sorger D, Scheunemann M, Stöcklin G. Patt M, et al. Among authors: sorger d. Appl Radiat Isot. 2002 Nov;57(5):705-12. doi: 10.1016/s0969-8043(02)00186-0. Appl Radiat Isot. 2002. PMID: 12433045

8

Alterations in cholinergic and non-cholinergic neurotransmitter receptor densities in transgenic Tg2576 mouse brain with beta-amyloid plaque pathology.

Klingner M, Apelt J, Kumar A, Sorger D, Sabri O, Steinbach J, Scheunemann M, Schliebs R. Klingner M, et al. Among authors: sorger d. Int J Dev Neurosci. 2003 Nov;21(7):357-69. doi: 10.1016/j.ijdevneu.2003.08.001. Int J Dev Neurosci. 2003. PMID: 14599482

9

Binding properties of the cerebral alpha4beta2 nicotinic acetylcholine receptor ligand 2-[18F]fluoro-A-85380 to plasma proteins.

Sorger D, Becker GA, Hauber K, Schildan A, Patt M, Birkenmeier G, Otto A, Meyer P, Kluge M, Schliebs R, Sabri O. Sorger D, et al. Nucl Med Biol. 2006 Oct;33(7):899-906. doi: 10.1016/j.nucmedbio.2006.07.012. Nucl Med Biol. 2006. PMID: 17045170 Clinical Trial.

10

In vivo measurement of nicotinic acetylcholine receptors with [18F]norchloro-fluoro-homoepibatidine.

Brust P, Patt JT, Deuther-Conrad W, Becker G, Patt M, Schildan A, Sorger D, Kendziorra K, Meyer P, Steinbach J, Sabri O. Brust P, et al. Among authors: sorger d. Synapse. 2008 Mar;62(3):205-18. doi: 10.1002/syn.20480. Synapse. 2008. PMID: 18088060

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