Steinbach J - Search Results

1

Synthesis of novel 4- and 5-substituted benzyl ether derivatives of vesamicol and in vitro evaluation of their binding properties to the vesicular acetylcholine transporter site.

Scheunemann M, Sorger D, Wenzel B, Heinitz K, Schliebs R, Klingner M, Sabri O, Steinbach J. Scheunemann M, et al. Among authors: steinbach j. Bioorg Med Chem. 2004 Mar 15;12(6):1459-65. doi: 10.1016/j.bmc.2003.12.035. Bioorg Med Chem. 2004. PMID: 15018919

2

New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET.

Vercouillie J, Deuther-Conrad W, Scheunemann M, Emond P, Fischer S, Funke U, Steinbach J, Guilloteau D, Brust P. Vercouillie J, et al. Among authors: steinbach j. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4991-5. doi: 10.1016/j.bmcl.2007.02.082. Epub 2007 Mar 7. Bioorg Med Chem Lett. 2007. PMID: 17658253

3

A new 18F-labeled fluoroacetylmorpholino derivative of vesamicol for neuroimaging of the vesicular acetylcholine transporter.

Sorger D, Scheunemann M, Grossmann U, Fischer S, Vercouille J, Hiller A, Wenzel B, Roghani A, Schliebs R, Brust P, Sabri O, Steinbach J. Sorger D, et al. Among authors: steinbach j. Nucl Med Biol. 2008 Feb;35(2):185-95. doi: 10.1016/j.nucmedbio.2007.10.004. Nucl Med Biol. 2008. PMID: 18312828

4

First CoMFA characterization of vesamicol analogs as ligands for the vesicular acetylcholine transporter.

Szymoszek A, Wenzel B, Scheunemann M, Steinbach J, Schüürmann G. Szymoszek A, et al. Among authors: steinbach j. J Med Chem. 2008 Apr 10;51(7):2128-36. doi: 10.1021/jm700961r. Epub 2008 Mar 7. J Med Chem. 2008. PMID: 18324757

5

3-(4-(6-Fluoroalkoxy-3,4-dihydroisoquinoline-2(1H)-yl)cyclohexyl)-1H-indole-5-carbonitriles for SERT imaging: chemical synthesis, evaluation in vitro and radiofluorination.

Funke U, Fischer S, Hiller A, Scheunemann M, Deuther-Conrad W, Brust P, Steinbach J. Funke U, et al. Among authors: steinbach j. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4727-30. doi: 10.1016/j.bmcl.2008.06.077. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18644726

6

Pyrrolovesamicols--synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers.

Wenzel B, Li Y, Kraus W, Sorger D, Sabri O, Brust P, Steinbach J. Wenzel B, et al. Among authors: steinbach j. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2163-6. doi: 10.1016/j.bmcl.2012.01.127. Epub 2012 Feb 4. Bioorg Med Chem Lett. 2012. PMID: 22365760

7

New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure.

Barthel C, Sorger D, Deuther-Conrad W, Scheunemann M, Schweiger S, Jäckel P, Roghani A, Steinbach J, Schüürmann G, Sabri O, Brust P, Wenzel B. Barthel C, et al. Among authors: steinbach j. Eur J Med Chem. 2015 Jul 15;100:50-67. doi: 10.1016/j.ejmech.2015.05.033. Epub 2015 May 22. Eur J Med Chem. 2015. PMID: 26071858

8

Structural changes of benzylether derivatives of vesamicol and their influence on the binding selectivity to the vesicular acetylcholine transporter.

Wenzel B, Sorger D, Heinitz K, Scheunemann M, Schliebs R, Steinbach J, Sabri O. Wenzel B, et al. Among authors: steinbach j. Eur J Med Chem. 2005 Dec;40(12):1197-205. doi: 10.1016/j.ejmech.2005.06.007. Epub 2005 Aug 10. Eur J Med Chem. 2005. PMID: 16095762

9

Neuroimaging of the vesicular acetylcholine transporter by a novel 4-[18F]fluoro-benzoyl derivative of 7-hydroxy-6-(4-phenyl-piperidin-1-yl)-octahydro-benzo[1,4]oxazines.

Sorger D, Scheunemann M, Vercouillie J, Grossmann U, Fischer S, Hiller A, Wenzel B, Roghani A, Schliebs R, Steinbach J, Brust P, Sabri O. Sorger D, et al. Among authors: steinbach j. Nucl Med Biol. 2009 Jan;36(1):17-27. doi: 10.1016/j.nucmedbio.2008.10.006. Nucl Med Biol. 2009. PMID: 19181265

10

Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors.

Smits R, Fischer S, Hiller A, Deuther-Conrad W, Wenzel B, Patt M, Cumming P, Steinbach J, Sabri O, Brust P, Hoepping A. Smits R, et al. Among authors: steinbach j. Bioorg Med Chem. 2014 Jan 15;22(2):804-12. doi: 10.1016/j.bmc.2013.12.011. Epub 2013 Dec 12. Bioorg Med Chem. 2014. PMID: 24369841

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