Wu K - Search Results

1

Nedd8 on cullin: building an expressway to protein destruction.

Pan ZQ, Kentsis A, Dias DC, Yamoah K, Wu K. Pan ZQ, et al. Among authors: wu k. Oncogene. 2004 Mar 15;23(11):1985-97. doi: 10.1038/sj.onc.1207414. Oncogene. 2004. PMID: 15021886 Review.

2

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.

Tan P, Fuchs SY, Chen A, Wu K, Gomez C, Ronai Z, Pan ZQ. Tan P, et al. Among authors: wu k. Mol Cell. 1999 Apr;3(4):527-33. doi: 10.1016/s1097-2765(00)80481-5. Mol Cell. 1999. PMID: 10230406 Free article.

3

The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation.

Wu K, Fuchs SY, Chen A, Tan P, Gomez C, Ronai Z, Pan ZQ. Wu K, et al. Mol Cell Biol. 2000 Feb;20(4):1382-93. doi: 10.1128/MCB.20.4.1382-1393.2000. Mol Cell Biol. 2000. PMID: 10648623 Free PMC article.

4

The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation.

Chen A, Wu K, Fuchs SY, Tan P, Gomez C, Pan ZQ. Chen A, et al. Among authors: wu k. J Biol Chem. 2000 May 19;275(20):15432-9. doi: 10.1074/jbc.M907300199. J Biol Chem. 2000. PMID: 10748083 Free article.

5

Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization.

Wu K, Chen A, Pan ZQ. Wu K, et al. J Biol Chem. 2000 Oct 13;275(41):32317-24. doi: 10.1074/jbc.M004847200. J Biol Chem. 2000. PMID: 10921923 Free article.

6

The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34.

Wu K, Chen A, Tan P, Pan ZQ. Wu K, et al. J Biol Chem. 2002 Jan 4;277(1):516-27. doi: 10.1074/jbc.M108008200. Epub 2001 Oct 23. J Biol Chem. 2002. PMID: 11675391 Free article.

7

Identification and characterization of DEN1, a deneddylase of the ULP family.

Gan-Erdene T, Nagamalleswari K, Yin L, Wu K, Pan ZQ, Wilkinson KD. Gan-Erdene T, et al. Among authors: wu k. J Biol Chem. 2003 Aug 1;278(31):28892-900. doi: 10.1074/jbc.M302890200. Epub 2003 May 19. J Biol Chem. 2003. PMID: 12759362 Free article.

8

DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1.

Wu K, Yamoah K, Dolios G, Gan-Erdene T, Tan P, Chen A, Lee CG, Wei N, Wilkinson KD, Wang R, Pan ZQ. Wu K, et al. J Biol Chem. 2003 Aug 1;278(31):28882-91. doi: 10.1074/jbc.M302888200. Epub 2003 May 19. J Biol Chem. 2003. PMID: 12759363 Free article.

9

Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1.

Reverter D, Wu K, Erdene TG, Pan ZQ, Wilkinson KD, Lima CD. Reverter D, et al. Among authors: wu k. J Mol Biol. 2005 Jan 7;345(1):141-51. doi: 10.1016/j.jmb.2004.10.022. J Mol Biol. 2005. PMID: 15567417

10

Identification of mutations in CUL7 in 3-M syndrome.

Huber C, Dias-Santagata D, Glaser A, O'Sullivan J, Brauner R, Wu K, Xu X, Pearce K, Wang R, Uzielli ML, Dagoneau N, Chemaitilly W, Superti-Furga A, Dos Santos H, Mégarbané A, Morin G, Gillessen-Kaesbach G, Hennekam R, Van der Burgt I, Black GC, Clayton PE, Read A, Le Merrer M, Scambler PJ, Munnich A, Pan ZQ, Winter R, Cormier-Daire V. Huber C, et al. Among authors: wu k. Nat Genet. 2005 Oct;37(10):1119-24. doi: 10.1038/ng1628. Epub 2005 Sep 4. Nat Genet. 2005. PMID: 16142236

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