Clapham DE - Search Results

1

A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway.

Xu H, Jin J, DeFelice LJ, Andrews NC, Clapham DE. Xu H, et al. Among authors: clapham de. PLoS Biol. 2004 Mar;2(3):E50. doi: 10.1371/journal.pbio.0020050. Epub 2004 Mar 16. PLoS Biol. 2004. PMID: 15024413 Free PMC article.

2

TRP ion channels in the nervous system.

Moran MM, Xu H, Clapham DE. Moran MM, et al. Among authors: clapham de. Curr Opin Neurobiol. 2004 Jun;14(3):362-9. doi: 10.1016/j.conb.2004.05.003. Curr Opin Neurobiol. 2004. PMID: 15194117 Review.

3

Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism.

Xu H, Blair NT, Clapham DE. Xu H, et al. Among authors: clapham de. J Neurosci. 2005 Sep 28;25(39):8924-37. doi: 10.1523/JNEUROSCI.2574-05.2005. J Neurosci. 2005. PMID: 16192383 Free PMC article.

4

Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.

Xu H, Delling M, Li L, Dong X, Clapham DE. Xu H, et al. Among authors: clapham de. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18321-6. doi: 10.1073/pnas.0709096104. Epub 2007 Nov 7. Proc Natl Acad Sci U S A. 2007. PMID: 17989217 Free PMC article.

5

Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis.

Jin J, Desai BN, Navarro B, Donovan A, Andrews NC, Clapham DE. Jin J, et al. Among authors: clapham de. Science. 2008 Oct 31;322(5902):756-60. doi: 10.1126/science.1163493. Science. 2008. PMID: 18974357 Free PMC article.

6

The channel kinase, TRPM7, is required for early embryonic development.

Jin J, Wu LJ, Jun J, Cheng X, Xu H, Andrews NC, Clapham DE. Jin J, et al. Among authors: clapham de. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):E225-33. doi: 10.1073/pnas.1120033109. Epub 2011 Dec 27. Proc Natl Acad Sci U S A. 2012. PMID: 22203997 Free PMC article.

7

TRPV3 is a calcium-permeable temperature-sensitive cation channel.

Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE. Xu H, et al. Among authors: clapham de. Nature. 2002 Jul 11;418(6894):181-6. doi: 10.1038/nature00882. Epub 2002 Jun 23. Nature. 2002. PMID: 12077604

8

Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels.

Xu H, Delling M, Jun JC, Clapham DE. Xu H, et al. Among authors: clapham de. Nat Neurosci. 2006 May;9(5):628-35. doi: 10.1038/nn1692. Epub 2006 Apr 16. Nat Neurosci. 2006. PMID: 16617338

9

Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.

Zhuang ZY, Xu H, Clapham DE, Ji RR. Zhuang ZY, et al. Among authors: clapham de. J Neurosci. 2004 Sep 22;24(38):8300-9. doi: 10.1523/JNEUROSCI.2893-04.2004. J Neurosci. 2004. PMID: 15385613 Free PMC article.

10

A superfamily of voltage-gated sodium channels in bacteria.

Koishi R, Xu H, Ren D, Navarro B, Spiller BW, Shi Q, Clapham DE. Koishi R, et al. Among authors: clapham de. J Biol Chem. 2004 Mar 5;279(10):9532-8. doi: 10.1074/jbc.M313100200. Epub 2003 Dec 9. J Biol Chem. 2004. PMID: 14665618 Free article.

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