Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

78 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Potent, selective, and orally active adenosine A2A receptor antagonists: arylpiperazine derivatives of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines.
Neustadt BR, Hao J, Lindo N, Greenlee WJ, Stamford AW, Tulshian D, Ongini E, Hunter J, Monopoli A, Bertorelli R, Foster C, Arik L, Lachowicz J, Ng K, Feng KI. Neustadt BR, et al. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1376-80. doi: 10.1016/j.bmcl.2006.11.083. Epub 2006 Dec 3. Bioorg Med Chem Lett. 2007. PMID: 17236762
Substituted 2-(R)-methyl piperazines as muscarinic M(2) selective ligands.
Kozlowski JA, Zhou G, Tagat JR, Lin SI, McCombie SW, Ruperto VB, Duffy RA, McQuade RA, Crosby G, Taylor LA, Billard W, Binch H, Lachowicz JE. Kozlowski JA, et al. Among authors: lachowicz je. Bioorg Med Chem Lett. 2002 Mar 11;12(5):791-4. doi: 10.1016/s0960-894x(02)00023-9. Bioorg Med Chem Lett. 2002. PMID: 11859004
Synthesis and structure-activity relationships of M(2)-selective muscarinic receptor ligands in the 1-[4-(4-arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family.
McCombie SW, Lin SI, Tagat JR, Nazareno D, Vice S, Ford J, Asberom T, Leone D, Kozlowski JA, Zhou G, Ruperto VB, Duffy RA, Lachowicz JE. McCombie SW, et al. Among authors: lachowicz je. Bioorg Med Chem Lett. 2002 Mar 11;12(5):795-8. doi: 10.1016/s0960-894x(02)00024-0. Bioorg Med Chem Lett. 2002. PMID: 11859005
Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M(2) muscarinic receptor antagonists via benzamide modification.
Boyle CD, Vice SF, Campion J, Chackalamannil S, Lankin CM, McCombie SW, Billard W, Binch H 3rd, Crosby G, Williams MC, Coffin VL, Cox KA, Grotz DE, Duffy RA, Ruperto V, Lachowicz JE. Boyle CD, et al. Among authors: lachowicz je. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3479-82. doi: 10.1016/s0960-894x(02)00742-4. Bioorg Med Chem Lett. 2002. PMID: 12419388
Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists.
Wang Y, Chackalamannil S, Hu Z, Greenlee WJ, Clader J, Boyle CD, Kaminski JJ, Billard W, Binch H 3rd, Crosby G, Ruperto V, Duffy RA, Cohen-Williams M, Coffin VL, Cox KA, Grotz DE, Lachowicz JE. Wang Y, et al. Among authors: lachowicz je. J Med Chem. 2002 Dec 5;45(25):5415-8. doi: 10.1021/jm0255163. J Med Chem. 2002. PMID: 12459007
78 results