McGuigan C - Search Results

1

Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.

McGuigan C, Pathirana RN, Snoeck R, Andrei G, De Clercq E, Balzarini J. McGuigan C, et al. J Med Chem. 2004 Mar 25;47(7):1847-51. doi: 10.1021/jm030857h. J Med Chem. 2004. PMID: 15027877

2

Alkyloxyphenyl furano pyrimidines as potent and selective anti-VZV agents with enhanced water solubility.

McGuigan C, Blewett S, Siccardi D, Erichsen JT, Andrei G, Snoek R, De Clercq E, Balzarini J. McGuigan C, et al. Antivir Chem Chemother. 2002 Mar;13(2):91-9. doi: 10.1177/095632020201300203. Antivir Chem Chemother. 2002. PMID: 12238533 Free article.

3

Halophenyl furanopyrimidines as potent and selective anti-VZV agents.

McGuigan C, Jukes A, Blewett S, Barucki H, Erichsen JT, Andrei G, Snoeck R, De Clercq E, Balzarini J. McGuigan C, et al. Antivir Chem Chemother. 2003 May;14(3):165-70. doi: 10.1177/095632020301400306. Antivir Chem Chemother. 2003. PMID: 14521333 Free article.

4

Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activity.

McGuigan C, Brancale A, Andrei G, Snoeck R, De Clercq E, Balzarini J. McGuigan C, et al. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4511-3. doi: 10.1016/j.bmcl.2003.08.028. Bioorg Med Chem Lett. 2003. PMID: 14643358

5

Synthesis and antiviral evaluation of some 3'-fluoro bicyclic nucleoside analogues.

McGuigan C, Carangio A, Snoeck R, Andrei G, De Clercq E, Balzarini J. McGuigan C, et al. Nucleosides Nucleotides Nucleic Acids. 2004;23(1-2):1-5. doi: 10.1081/ncn-120027813. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15043132

6

Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity.

Angell A, McGuigan C, Garcia Sevillano L, Snoeck R, Andrei G, De Clercq E, Balzarini J. Angell A, et al. Among authors: mcguigan c. Bioorg Med Chem Lett. 2004 May 17;14(10):2397-9. doi: 10.1016/j.bmcl.2004.03.029. Bioorg Med Chem Lett. 2004. PMID: 15109620

7

Non-nucleoside structures retain full anti-HCMV potency of the dideoxy furanopyrimidine family.

Bidet O, McGuigan C, Snoeck R, Andrei G, De Clercq E, Balzarini J. Bidet O, et al. Among authors: mcguigan c. Antivir Chem Chemother. 2004 Nov;15(6):329-32. doi: 10.1177/095632020401500605. Antivir Chem Chemother. 2004. PMID: 15646646 Free article.

8

Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.

Luoni GM, McGuigan C, Andrei G, Snoeck R, De Clercq E, Balzarini J. Luoni GM, et al. Among authors: mcguigan c. Antivir Chem Chemother. 2004 Nov;15(6):333-41. doi: 10.1177/095632020401500606. Antivir Chem Chemother. 2004. PMID: 15646647 Free article.

9

Application of phosphoramidate pronucleotide technology to abacavir leads to a significant enhancement of antiviral potency.

McGuigan C, Harris SA, Daluge SM, Gudmundsson KS, McLean EW, Burnette TC, Marr H, Hazen R, Condreay LD, Johnson L, De Clercq E, Balzarini J. McGuigan C, et al. J Med Chem. 2005 May 19;48(10):3504-15. doi: 10.1021/jm0491400. J Med Chem. 2005. PMID: 15887959

10

Bicyclic nucleoside inhibitors of Varicella-Zoster virus: the effect of branching in the p-alkylphenyl side chain.

Luoni G, McGuigan C, Andrei G, Snoeck R, De Clercq E, Balzarini J. Luoni G, et al. Among authors: mcguigan c. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3791-6. doi: 10.1016/j.bmcl.2005.05.071. Bioorg Med Chem Lett. 2005. PMID: 15993062

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