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Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension.
Ghofrani HA, Rose F, Schermuly RT, Olschewski H, Wiedemann R, Weissmann N, Schudt C, Tenor H, Seeger W, Grimminger F. Ghofrani HA, et al. Among authors: schudt c. Crit Care Med. 2002 Nov;30(11):2489-92. doi: 10.1097/00003246-200211000-00014. Crit Care Med. 2002. PMID: 12441759 Clinical Trial.
Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.
Schermuly RT, Pullamsetti SS, Kwapiszewska G, Dumitrascu R, Tian X, Weissmann N, Ghofrani HA, Kaulen C, Dunkern T, Schudt C, Voswinckel R, Zhou J, Samidurai A, Klepetko W, Paddenberg R, Kummer W, Seeger W, Grimminger F. Schermuly RT, et al. Among authors: schudt c. Circulation. 2007 May 1;115(17):2331-9. doi: 10.1161/CIRCULATIONAHA.106.676809. Epub 2007 Apr 16. Circulation. 2007. PMID: 17438150
cAMP phosphodiesterase inhibitors increases nitric oxide production by modulating dimethylarginine dimethylaminohydrolases.
Pullamsetti SS, Savai R, Schaefer MB, Wilhelm J, Ghofrani HA, Weissmann N, Schudt C, Fleming I, Mayer K, Leiper J, Seeger W, Grimminger F, Schermuly RT. Pullamsetti SS, et al. Among authors: schudt c. Circulation. 2011 Mar 22;123(11):1194-204. doi: 10.1161/CIRCULATIONAHA.110.941484. Epub 2011 Mar 7. Circulation. 2011. PMID: 21382892
Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity.
Schermuly RT, Krupnik E, Tenor H, Schudt C, Weissmann N, Rose F, Grimminger F, Seeger W, Walmrath D, Ghofrani HA. Schermuly RT, et al. Among authors: schudt c. Am J Respir Crit Care Med. 2001 Nov 1;164(9):1694-700. doi: 10.1164/ajrccm.164.9.2105060. Am J Respir Crit Care Med. 2001. PMID: 11719312
Zardaverine and aerosolised iloprost in a model of acute respiratory failure.
Schermuly RT, Leuchte H, Ghofrani HA, Weissmann N, Rose F, Kohstall M, Olschewski H, Schudt C, Grimminger F, Seeger W, Walmrath D. Schermuly RT, et al. Among authors: schudt c. Eur Respir J. 2003 Aug;22(2):342-7. doi: 10.1183/09031936.03.00093802. Eur Respir J. 2003. PMID: 12952271 Free article.
85 results