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Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action.
Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Zabolotny JM, et al. Among authors: kim jk, kim hj, kim yb. J Biol Chem. 2004 Jun 4;279(23):24844-51. doi: 10.1074/jbc.M310688200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15031294 Free article.
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle.
Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, Bergeron R, Kim JK, Cushman SW, Cooney GJ, Atcheson B, White MF, Kraegen EW, Shulman GI. Yu C, et al. Among authors: kim jk. J Biol Chem. 2002 Dec 27;277(52):50230-6. doi: 10.1074/jbc.M200958200. Epub 2002 Nov 14. J Biol Chem. 2002. PMID: 12006582 Free article.
PKC-theta knockout mice are protected from fat-induced insulin resistance.
Kim JK, Fillmore JJ, Sunshine MJ, Albrecht B, Higashimori T, Kim DW, Liu ZX, Soos TJ, Cline GW, O'Brien WR, Littman DR, Shulman GI. Kim JK, et al. Among authors: kim dw. J Clin Invest. 2004 Sep;114(6):823-7. doi: 10.1172/JCI22230. J Clin Invest. 2004. PMID: 15372106 Free PMC article.
5,513 results