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Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells.
Marchesini N, Osta W, Bielawski J, Luberto C, Obeid LM, Hannun YA. Marchesini N, et al. J Biol Chem. 2004 Jun 11;279(24):25101-11. doi: 10.1074/jbc.M313662200. Epub 2004 Mar 29. J Biol Chem. 2004. PMID: 15051724 Free article.
Recently, we reported that neutral sphingomyelinase 2 (nSMase2) functions as a bona fide neutral sphingomyelinase and that overexpression of nSMase2 in MCF7 breast cancer cells caused a decrease in cell growth (Marchesini, N., Luberto, C., and Hannun, Y. A. (2003) J …
Recently, we reported that neutral sphingomyelinase 2 (nSMase2) functions as a bona fide neutral sphingomyelinase and that overexpression of …
Confluence induced threonine41/serine45 phospho-beta-catenin dephosphorylation via ceramide-mediated activation of PP1cgamma.
Marchesini N, Jones JA, Hannun YA. Marchesini N, et al. Biochim Biophys Acta. 2007 Dec;1771(12):1418-28. doi: 10.1016/j.bbalip.2007.10.003. Epub 2007 Nov 8. Biochim Biophys Acta. 2007. PMID: 17996206 Free PMC article.
It was previously observed that cell confluence induced up-regulation of neutral sphingomyelinase 2 (nSMase2) and increased ceramide levels [Marchesini N., Osta W., Bielawski J., Luberto C., Obeid L.M. and Hannun Y.A. (2004) J. Biol. ...
It was previously observed that cell confluence induced up-regulation of neutral sphingomyelinase 2 (nSMase2) and increased ceramide levels …
The extended family of neutral sphingomyelinases.
Clarke CJ, Snook CF, Tani M, Matmati N, Marchesini N, Hannun YA. Clarke CJ, et al. Among authors: marchesini n. Biochemistry. 2006 Sep 26;45(38):11247-56. doi: 10.1021/bi061307z. Biochemistry. 2006. PMID: 16981685 Review.
The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase.
Philipp S, Puchert M, Adam-Klages S, Tchikov V, Winoto-Morbach S, Mathieu S, Deerberg A, Kolker L, Marchesini N, Kabelitz D, Hannun YA, Schütze S, Adam D. Philipp S, et al. Among authors: marchesini n. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1112-7. doi: 10.1073/pnas.0908486107. Epub 2009 Dec 28. Proc Natl Acad Sci U S A. 2010. PMID: 20080539 Free PMC article.
45 results