Brouillette W - Search Results

1

Syntheses and neuraminidase inhibitory activity of multisubstituted cyclopentane amide derivatives.

Chand P, Babu YS, Bantia S, Rowland S, Dehghani A, Kotian PL, Hutchison TL, Ali S, Brouillette W, El-Kattan Y, Lin TH. Chand P, et al. Among authors: brouillette w. J Med Chem. 2004 Apr 8;47(8):1919-29. doi: 10.1021/jm0303406. J Med Chem. 2004. PMID: 15055992

2

Synthesis of 2-[6-(2,4-dinitrophenoxy)hexyl]oxiranecarboxylic acid: a selective carnitine palmitoyltransferase-1 inhibitor.

Hutchison TL, Brouillette WJ. Hutchison TL, et al. Among authors: brouillette wj. Bioorg Med Chem. 1998 Nov;6(11):2133-8. doi: 10.1016/s0968-0896(98)00175-8. Bioorg Med Chem. 1998. PMID: 9881103

3

Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent.

Atigadda VR, Brouillette WJ, Duarte F, Ali SM, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Sudbeck EA, Finley J, Luo M, Air GM, Laver GW. Atigadda VR, et al. Among authors: brouillette wj. J Med Chem. 1999 Jul 1;42(13):2332-43. doi: 10.1021/jm980707k. J Med Chem. 1999. PMID: 10395473

4

Design of benzoic acid inhibitors of influenza neuraminidase containing a cyclic substitution for the N-acetyl grouping.

Brouillette WJ, Atigadda VR, Luo M, Air GM, Babu YS, Bantia S. Brouillette WJ, et al. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1901-6. doi: 10.1016/s0960-894x(99)00318-2. Bioorg Med Chem Lett. 1999. PMID: 10450950

5

Hydrophobic benzoic acids as inhibitors of influenza neuraminidase.

Atigadda VR, Brouillette WJ, Duarte F, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Sudbeck E, Finley J, Air GM, Luo M, Laver GW. Atigadda VR, et al. Among authors: brouillette wj. Bioorg Med Chem. 1999 Nov;7(11):2487-97. doi: 10.1016/s0968-0896(99)00197-2. Bioorg Med Chem. 1999. PMID: 10632058

6

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

Brouillette WJ, Bajpai SN, Ali SM, Velu SE, Atigadda VR, Lommer BS, Finley JB, Luo M, Air GM. Brouillette WJ, et al. Bioorg Med Chem. 2003 Jul 3;11(13):2739-49. doi: 10.1016/s0968-0896(03)00271-2. Bioorg Med Chem. 2003. PMID: 12788348

7

Stereoselective synthesis of a conformationally defined cyclohexyl carnitine analogue that binds CPT-1 with high affinity.

Hutchison TL, Saeed A, Wolkowicz PE, McMillin JB, Brouillette WJ. Hutchison TL, et al. Among authors: brouillette wj. Bioorg Med Chem. 1999 Aug;7(8):1505-11. doi: 10.1016/s0968-0896(99)00080-2. Bioorg Med Chem. 1999. PMID: 10482442

8

A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase.

Lommer BS, Ali SM, Bajpai SN, Brouillette WJ, Air GM, Luo M. Lommer BS, et al. Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1017-23. doi: 10.1107/S0907444904006225. Epub 2004 May 21. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15159560

9

Guanidinobenzoic acid inhibitors of influenza virus neuraminidase.

Sudbeck EA, Jedrzejas MJ, Singh S, Brouillette WJ, Air GM, Laver WG, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Luo M. Sudbeck EA, et al. Among authors: brouillette wj. J Mol Biol. 1997 Apr 4;267(3):584-94. doi: 10.1006/jmbi.1996.0885. J Mol Biol. 1997. PMID: 9126840

10

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: the hydrophobic side chain influences type A subtype selectivity.

Li Y, Silamkoti A, Kolavi G, Mou L, Gulati S, Air GM, Brouillette WJ. Li Y, et al. Among authors: brouillette wj. Bioorg Med Chem. 2012 Jul 15;20(14):4582-9. doi: 10.1016/j.bmc.2012.05.001. Epub 2012 May 17. Bioorg Med Chem. 2012. PMID: 22677529 Free PMC article.

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